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IRS1 抗体 (pTyr1179) (Alexa Fluor 488)

IRS1 适用: 人, 小鼠, 大鼠 FACS, IF (cc) 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN6978031
发货至: 中国
  • 抗原 See all IRS1 抗体
    IRS1 (Insulin Receptor Substrate 1 (IRS1))
    抗原表位
    • 30
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    pTyr1179
    适用
    • 286
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    • 204
    • 23
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    • 15
    • 2
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    人, 小鼠, 大鼠
    宿主
    • 286
    • 12
    克隆类型
    • 280
    • 18
    多克隆
    标记
    • 133
    • 14
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    This IRS1 antibody is conjugated to Alexa Fluor 488
    应用范围
    • 167
    • 125
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    • 92
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    • 50
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    Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthesised phosphopeptide derived from human IRS1 around the phosphorylation site of Ser1179.
    亚型
    IgG
    Top Product
    Discover our top product IRS1 Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IRS1 (Insulin Receptor Substrate 1 (IRS1))
    别名
    IRS1 (IRS1 产品)
    别名
    HIRS-1 antibody, G972R antibody, IRS-1 antibody, IRS1IRM antibody, irs1 antibody, irsu antibody, IRS1 antibody, irs-1 antibody, irs1-a antibody, insulin receptor substrate 1 antibody, insulin receptor substrate 2 antibody, insulin receptor substrate 1 S homeolog antibody, IRS1 antibody, Irs1 antibody, irs2 antibody, irs1.S antibody
    背景

    Synonyms: IRS1 (phospho S1179), p-IRS1 (phospho S1179), p-IRS1, IRS1(phospho-Ser1179), HIRS 1, HIRS1, Insulin Receptor Substrate 1, IRS-1, IRS 1, IRS1, OTTHUMP00000164234, IRS1_HUMAN.

    Background: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.

    基因ID
    3667
    UniProt
    P35568
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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