IRS1 抗体 (pSer307)
(3 references)-
- 抗原 See all IRS1 抗体
- IRS1 (Insulin Receptor Substrate 1 (IRS1))
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抗原表位
- pSer307
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适用
- 人, 小鼠, 大鼠, 猴
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IRS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Phospho-IRS-1 (Ser307) Antibody detects endogenous levels of IRS-1 only when phosphorylated at Serine 307
- 交叉反应
- 人, 猴, 小鼠, 大鼠
- 纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- 免疫原
- A synthesized peptide derived from human IRS-1 around the phosphorylation site of Serine 307
- 亚型
- IgG
- Top Product
- Discover our top product IRS1 Primary Antibody
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anti-Insulin Receptor Substrate 1 (IRS1) (pSer636) antibody
IRS1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer639) antibodyIRS1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer312) antibodyIRS1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (AA 1041-1242) antibodyIRS1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (AA 106-122), (N-Term) antibodyIRS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer636) antibodyIRS1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (Ser312) antibodyIRS1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer312) antibodyIRS1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, DB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pTyr612) antibodyIRS1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, DB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (AA 274-323), (pSer307) antibodyIRS1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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: "P53 modulates hepatic insulin sensitivity through NF-κB and p38/ERK MAPK pathways." in: Biochemical and biophysical research communications, Vol. 495, Issue 3, pp. 2139-2144, (2018) (PubMed).
: "Curcumin suppresses JNK pathway to attenuate BPA-induced insulin resistance in LO2 cells." in: Biomedicine & pharmacotherapy, Vol. 97, pp. 1538-1543, (2018) (PubMed).
: "Curcumin attenuates BPA-induced insulin resistance in HepG2 cells through suppression of JNK/p38 pathways." in: Toxicology letters, Vol. 272, pp. 75-83, (2017) (PubMed).
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: "P53 modulates hepatic insulin sensitivity through NF-κB and p38/ERK MAPK pathways." in: Biochemical and biophysical research communications, Vol. 495, Issue 3, pp. 2139-2144, (2018) (PubMed).
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- 抗原
- IRS1 (Insulin Receptor Substrate 1 (IRS1))
- 别名
- IRS-1 (IRS1 产品)
- 别名
- HIRS-1 antibody, G972R antibody, IRS-1 antibody, IRS1IRM antibody, irs1 antibody, irsu antibody, IRS1 antibody, irs-1 antibody, irs1-a antibody, insulin receptor substrate 1 antibody, insulin receptor substrate 2 antibody, insulin receptor substrate 1 S homeolog antibody, IRS1 antibody, Irs1 antibody, irs2 antibody, irs1.S antibody
- 背景
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Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
Gene: IRS1
- 分子量
- 180kDa
- 基因ID
- 3667
- UniProt
- P35568
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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