IRS1 抗体 (pSer307)
(1 reference)Our Local Distributor
北京 101111
Quick Overview for IRS1 抗体 (pSer307) (ABIN1531876)
抗原
See all IRS1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 274-323, pSer307
-
原理
- IRS-1 (phospho Ser307) Antibody
-
特异性
- Phospho-IRS-1 (S307) Polyclonal Antibody detects endogenous levels of IRS-1 protein only when phosphorylated at S307.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser307. AA range:274-323
-
亚型
- IgG
-
-
anti-Insulin Receptor Substrate 1 (IRS1) antibody
IRS1 适用: 人, 小鼠, 大鼠, Pig WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (AA 1041-1242) antibodyIRS1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (N-Term) antibodyIRS1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer307) antibodyIRS1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (Ser312) antibodyIRS1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer636) antibodyIRS1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (AA 1041-1242) antibodyIRS1 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 小鼠 Monoclonal 10I3 unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (AA 1192-1242) antibodyIRS1 适用: 人 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer639) antibodyIRS1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) antibodyIRS1 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 23GB6155 unconjugated Recombinant Antibody
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
-
: "Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells." in: PLoS ONE, Vol. 9, Issue 6, pp. e97868, (2014) (PubMed).
-
-
- IRS1 (Insulin Receptor Substrate 1 (IRS1))
-
别名
- IRS-1
-
背景
-
Synonyms: IRS1, Insulin receptor substrate 1, IRS-1
Background: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009],
Gene Name: IRS1
Protein Name: Insulin receptor substrate 1
-
分子量
- 131 kDa
-
基因ID
- 3667
-
OMIM
- 125853
-
UniProt
- P35568
-
途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
-
