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C-JUN 抗体 (AA 31-331)

This anti-C-JUN antibody is a 兔 多克隆 antibody detecting C-JUN in WB, ELISA, IHC (p), FACS, IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠 和 小鸡. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN671691
发货至: 中国

Quick Overview for C-JUN 抗体 (AA 31-331) (ABIN671691)

Key Features

  • High quality C-JUN Primary Antibody for the detection of JUN.
  • Reliable product with high standard validation data

抗原

See all C-JUN (JUN) 抗体
C-JUN (JUN) (Jun Proto-Oncogene (JUN))

适用

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人, 小鼠, 大鼠, 小鸡

宿主

  • 361
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克隆类型

  • 330
  • 58
多克隆

标记

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This C-JUN antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 31-331

    交叉反应

    小鸡, 人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Sheep,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human c-Jun

    亚型

    IgG

    Product Specific Information

    What can the C-JUN Antibody ABIN671691 be used for?
    This polyclonal C-JUN Antibody detects C-JUN. The C-JUN Antibody has been validated for various applications and can be used for the detection of C-JUN and derivatives by Western Blotting, ELISA, Immunohistochemistry (Paraffin-embedded Sections), Flow Cytometry, Immunofluorescence (Cultured Cells), Immunofluorescence (Paraffin-embedded Sections), Immunohistochemistry (Frozen Sections).
    What validation data is available for this C-JUN Antibody?
    The Primary Antibody is referenced in 5 publications and is characterized by a proven, very high reliability. It has currently 6 product images that show its performance in a variety of applications. C-JUN Antibody for the detection of C-JUN and derivatives.
    What is the function of C-JUN?
    This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008].
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Liu, Lv, Ning, Yang, Zhu: "Therapeutic effects of 1,25-dihydroxyvitamin D3 on diabetes-induced liver complications in a rat model." in: Experimental and therapeutic medicine, Vol. 11, Issue 6, pp. 2284-2292, (2016) (PubMed).

    Zhou, Lu, Wang, Xiao, Liu, Xing: "microRNA let-7c is essential for the anisomycin-elicited apoptosis in Jurkat T cells by linking JNK1/2 to AP-1/STAT1/STAT3 signaling." in: Scientific reports, Vol. 6, pp. 24434, (2016) (PubMed).

    Zhang, Lin, Jin, Lin, Cao, Zheng: "Overexpression of WNT5B promotes COLO 205 cell migration and invasion through the JNK signaling pathway." in: Oncology reports, Vol. 36, Issue 1, pp. 23-30, (2016) (PubMed).

    Du, Niu, Wang, Zhao, Kong, Zhang, Nan: "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." in: Molecular medicine reports, Vol. 13, Issue 3, pp. 2159-66, (2016) (PubMed).

    Zhang, Pan, Xu, Niu, Ma, Xu: "Interleukin 18 augments growth ability via NF-?B and p38/ATF2 pathways by targeting cyclin B1, cyclin B2, cyclin A2, and Bcl-2 in BRL-3A rat liver cells." in: Gene, Vol. 563, Issue 1, pp. 45-51, (2015) (PubMed).

  • 抗原

    C-JUN (JUN) (Jun Proto-Oncogene (JUN))

    别名

    c-Jun

    背景

    Synonyms: AP1, AP-1, c-Jun, Transcription factor AP-1, Activator protein 1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, JUN

    Background: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

    基因ID

    3725

    UniProt

    P05412

    途径

    MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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