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XPC 抗体

XPC 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6571696
发货至: 中国
  • 抗原 See all XPC 抗体
    XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
    适用
    • 46
    • 3
    • 3
    • 1
    宿主
    • 45
    • 5
    克隆类型
    • 46
    • 4
    多克隆
    标记
    • 27
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This XPC antibody is un-conjugated
    应用范围
    • 35
    • 25
    • 10
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human XPC (NP_004619.3).
    亚型
    IgG
    Top Product
    Discover our top product XPC Primary Antibody
  • 应用备注
    IHC 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
    别名
    XPC (XPC 产品)
    别名
    RAD4 antibody, XP3 antibody, XPCC antibody, XPC complex subunit, DNA damage recognition and repair factor antibody, xeroderma pigmentosum, complementation group C antibody, XPC antibody, Xpc antibody
    背景
    This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
    分子量

    Observed_MW: 130kDa

    Calculated_MW: 15kDa/101kDa/105kDa

    基因ID
    7508
    UniProt
    Q01831
    途径
    p53 Pathway, DNA Damage Repair
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