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- 抗原 See all TRAF2 抗体
- TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRAF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human TRAF2
- 亚型
- IgG
- Top Product
- Discover our top product TRAF2 Primary Antibody
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anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 1-300) antibody
TRAF2 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 238-491) antibodyTRAF2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (C-Term) antibodyVerified TRAF2 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 39-188) antibodyTRAF2 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 5C2C3 unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) antibodyTRAF2 适用: 人 WB, ELISA, IHC, IP, FACS 宿主: 兔 Monoclonal 9A5 unconjugated Recombinant Antibody
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 39-188) antibodyTRAF2 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4A12D9 unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 401-501) antibodyTRAF2 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 147-281) antibodyTRAF2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 1-501) antibodyTRAF2 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4C11 unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (C-Term) antibodyTRAF2 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500 - 1:2000 IF 1:20 - 1:100
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))
- 别名
- TRAF2 (TRAF2 产品)
- 别名
- MGC:45012 antibody, TRAP antibody, TRAP3 antibody, TANK antibody, AI325259 antibody, TNF-receptor-associated factor 2 antibody, conjugal transfer protein TraF antibody, TNF receptor associated factor 2 antibody, TNF receptor-associated factor 2 antibody, Tnf receptor-associated factor 2 antibody, LOC661716 antibody, traF2 antibody, TRAF2 antibody, Traf2 antibody
- 背景
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Synonyms: E3 ubiquitin-protein ligase TRAF2,MGC:45012,OTTHUMP00000022625,OTTHUMP00000064745,TNF receptor associated factor 2,TNF receptor-associated factor 2,TNF receptor-associated protein,TRAF 2,TRAF2,TRAF2,TRAP 3,TRAP,TRAP3,Tumor necrosis factor type 2 receptor associated protein 3,Tumor necrosis factor type 2 receptor-associated protein 3
Background: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.
- 分子量
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Observed_MW: 54kDa
Calculated_MW: 53kDa/54kDa/55kDa/61kDa
- 基因ID
- 7186
- UniProt
- Q12933
- 途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response, S100 Proteins
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