NR3C2 抗体 (Middle Region)
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- 抗原 See all NR3C2 抗体
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR3C2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- NR3 C2 antibody was raised against the middle region of NR3 2
- 纯化方法
- Purified
- 免疫原
- NR3 C2 antibody was raised using the middle region of NR3 2 corresponding to a region with amino acids RRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPP
- Top Product
- Discover our top product NR3C2 Primary Antibody
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- 应用备注
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WB: 1.25 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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NR3C2 Blocking Peptide, catalog no. 33R-8142, is also available for use as a blocking control in assays to test for specificity of this NR3C2 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NR0 2 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
- 别名
- NR3C2 (NR3C2 产品)
- 别名
- mr antibody, si:ch211-189l17.1 antibody, LOC100302443 antibody, NR3C2 antibody, LOC443144 antibody, MLR antibody, MR antibody, MCR antibody, NR3C2VIT antibody, Mlr antibody, mlr antibody, nuclear receptor subfamily 3, group C, member 2 antibody, nuclear receptor subfamily 3 group C member 2 antibody, mineralocorticoid receptor antibody, nuclear receptor subfamily 3 group C member 2 L homeolog antibody, nr3c2 antibody, NR3C2 antibody, LOC443144 antibody, Nr3c2 antibody, nr3c2.L antibody
- 背景
- NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
- 分子量
- 107 kDa (MW of target protein)
- 途径
- ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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