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NR3C2 抗体

NR3C2 适用: 人, 大鼠, 兔, 小鸡 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal H10E4C9F unconjugated
产品编号 ABIN396956
发货至: 中国
  • 抗原 See all NR3C2 抗体
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    适用
    • 57
    • 44
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    人, 大鼠, 兔, 小鸡
    宿主
    • 70
    • 4
    小鼠
    克隆类型
    • 70
    • 4
    单克隆
    标记
    • 26
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    • 3
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    This NR3C2 antibody is un-conjugated
    应用范围
    • 71
    • 39
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    • 3
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    品牌
    IHC-plus™
    特异性
    Recognizes human MR (mineralocorticoid receptor). Detects a band of ~116kD by Western Blot. Species cross-reactivity: Rat, rabbit and chicken.
    纯化方法
    Protein G purified
    免疫原
    Aldosterone.

    Type of Immunogen: Hapten
    克隆位点
    H10E4C9F
    亚型
    IgG1
    Top Product
    Discover our top product NR3C2 Primary Antibody
  • 应用备注
    Approved: IHC, IHC-P (1:50), WB (1:250)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working dilution for LS-B3162 was determined to be 1:50. Function: Blocks the binding of aldosterone to the MR.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.2, 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Li, Tian, Wang, Hu, Qin, Xu, Liu, Hao, Tian: "LINC01128 resisted acute myeloid leukemia through regulating miR-4260/NR3C2." in: Cancer biology & therapy, Vol. 21, Issue 7, pp. 615-622, (2020) (PubMed).

  • 抗原
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    别名
    Mineralocorticoid Receptor (NR3C2 产品)
    别名
    mr antibody, si:ch211-189l17.1 antibody, LOC100302443 antibody, NR3C2 antibody, LOC443144 antibody, MLR antibody, MR antibody, MCR antibody, NR3C2VIT antibody, Mlr antibody, mlr antibody, nuclear receptor subfamily 3, group C, member 2 antibody, nuclear receptor subfamily 3 group C member 2 antibody, mineralocorticoid receptor antibody, nuclear receptor subfamily 3 group C member 2 L homeolog antibody, nr3c2 antibody, NR3C2 antibody, LOC443144 antibody, Nr3c2 antibody, nr3c2.L antibody
    背景
    Name/Gene ID: NR3C2
    Subfamily: NR3 Steroid receptor
    Family: NHR

    Synonyms: NR3C2, MCR, Mineralocorticoid receptor, NR3C2VIT, Aldosterone receptor, Mineralocorticoid receptor 1, MLR, MR
    基因ID
    4306
    UniProt
    P08235
    途径
    ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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