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NR3C2 抗体 (C-Term)

NR3C2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1681109
发货至: 中国
  • 抗原 See all NR3C2 抗体
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    抗原表位
    • 16
    • 15
    • 15
    • 7
    • 3
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 58
    • 44
    • 30
    • 17
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    宿主
    • 69
    • 5
    克隆类型
    • 69
    • 5
    多克隆
    标记
    • 26
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
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    This NR3C2 antibody is un-conjugated
    应用范围
    • 71
    • 39
    • 39
    • 20
    • 14
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    • 10
    • 8
    • 3
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    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    SWQRFYQLTK LLDSMHDLVS DLLEFCFYTF RESHALKVEF PAMLVEIISD QLPKVESGNA KPLYFHRK
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 800 to the C-terminus of human Mineralocorticoid receptor (NR3C2) (NP_001159576.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    别名
    NR3C2 (NR3C2 产品)
    别名
    mr antibody, si:ch211-189l17.1 antibody, LOC100302443 antibody, NR3C2 antibody, LOC443144 antibody, MLR antibody, MR antibody, MCR antibody, NR3C2VIT antibody, Mlr antibody, mlr antibody, nuclear receptor subfamily 3, group C, member 2 antibody, nuclear receptor subfamily 3 group C member 2 antibody, mineralocorticoid receptor antibody, nuclear receptor subfamily 3 group C member 2 L homeolog antibody, nr3c2 antibody, NR3C2 antibody, LOC443144 antibody, Nr3c2 antibody, nr3c2.L antibody
    背景
    This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.,NR3C2,MCR,MLR,MR,NR3C2VIT,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,Cardiovascular,Heart,Hypertrophy,Cardiovascular diseases,Hypertension,NR3C2
    分子量
    75 kDa/94 kDa/107 kDa
    基因ID
    4306
    UniProt
    P08235
    途径
    ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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