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NR3C2 抗体 (AA 601-700)

NR3C2 适用: 人, 大鼠, 小鼠, 犬 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN735353
发货至: 中国
  • 抗原 See all NR3C2 抗体
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    抗原表位
    • 15
    • 15
    • 15
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-700
    适用
    • 57
    • 45
    • 29
    • 16
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    人, 大鼠, 小鼠, 犬
    宿主
    • 70
    • 5
    克隆类型
    • 69
    • 6
    多克隆
    标记
    • 27
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This NR3C2 antibody is un-conjugated
    应用范围
    • 72
    • 38
    • 38
    • 19
    • 13
    • 11
    • 9
    • 9
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
    交叉反应
    犬, 人, 小鼠, 大鼠
    预测反应
    Cow,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Mineralocorticoid receptor
    亚型
    IgG
    Top Product
    Discover our top product NR3C2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Liu, Jiang, Zhang, Li, Li, Xie, Hu: "Pulmonary artery denervation improves pulmonary arterial hypertension induced right ventricular dysfunction by modulating the local renin-angiotensin-aldosterone system." in: BMC cardiovascular disorders, Vol. 16, Issue 1, pp. 192, (2016) (PubMed).

  • 抗原
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    别名
    NR3C2/Mineralocorticoid receptor (NR3C2 产品)
    别名
    mr antibody, si:ch211-189l17.1 antibody, LOC100302443 antibody, NR3C2 antibody, LOC443144 antibody, MLR antibody, MR antibody, MCR antibody, NR3C2VIT antibody, Mlr antibody, mlr antibody, nuclear receptor subfamily 3, group C, member 2 antibody, nuclear receptor subfamily 3 group C member 2 antibody, mineralocorticoid receptor antibody, nuclear receptor subfamily 3 group C member 2 L homeolog antibody, nr3c2 antibody, NR3C2 antibody, LOC443144 antibody, Nr3c2 antibody, nr3c2.L antibody
    背景

    Synonyms: MR, MCR, MLR, NR3C2VIT, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2, NR3C2

    Background: Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.

    基因ID
    4306
    UniProt
    P08235
    途径
    ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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