我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

BAX 抗体 (Internal Region)

Name: BAX 抗体 (Internal Region)
SKU: ABIN6260204
Availability: OutOfStock

BAX 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis on HepG2 cell lysate using Bax Antibody. (BAX 抗体 (Internal Region))

IF/ICC

2 images

(3 references)

产品编号 ABIN6260204

发货至: 中国

Datasheet as PDF

抗原 See all BAX 抗体

BAX (BCL2-Associated X Protein (BAX))
抗原表位
39

32

19

18

15

11

10

10

9

8

8

7

6

6

5

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Internal Region
适用
257

154

142

46

31

27

25

18

17

10

9

5

3

3

3

2

1

1

1

1

1
人, 小鼠, 大鼠
宿主
168

96

4

2
兔
Compatible Secondaries
克隆类型
182

88
多克隆
标记
142

16

13

12

10

7

6

6

6

6

6

6

5

5

5

5

5

1

1

1

1

1

1

1

1

1
This BAX antibody is un-conjugated
应用范围
241

112

72

66

53

52

52

43

42

13

12

8

5

3

1

1

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

Bax Antibody detects endogenous levels of total Bax.

预测反应

Pig,Bovine,Horse,Rabbit,Dog

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human Bax, corresponding to a region within the internal amino acids.

亚型

IgG

Top Product

Discover our top product BAX Primary Antibody
anti-BCL2-Associated X Protein (BAX) (AA 84-175) antibody
BAX 适用: 人, 小鼠, 大鼠, Pig, Cow, 兔, 小鸡, 斑马鱼 WB, ELISA, FACS, IP, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 1-100) antibody
BAX 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) (N-Term) antibody
BAX 适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, 兔, 犬, 小鸡, 绵羊, 马, 豚鼠, Hamster, 山羊, Avian, Cat, 驴 WB, IF 宿主: 山羊 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) antibody
KO Validated BAX 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) antibody
BAX 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 1-158) antibody
BAX 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibody
BAX 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F5-1B7 unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibody
BAX 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 4H9B11 unconjugated

anti-BCL2-Associated X Protein (BAX) antibody
BAX 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2D8H2 unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibody
BAX 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB0952 unconjugated

应用备注

WB: 1:500-1:3000, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Mao, Du, Yang, Zhang, Peng, Jiang, Zhou: "Inhibitors of PARP-1 exert inhibitory effects on the biological characteristics of hepatocellular carcinoma cells in vitro." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 208-214, (2018) (PubMed).

Wang, Li, Li, Pan, Bai, Huang: "Angelicin inhibits liver cancer growth in vitro and in vivo." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 5441-5449, (2018) (PubMed).

Wu, Huang, Jiao, Ding, Zhang, Chen, Wang, Li, Huo: "Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells." in: Oncotarget, Vol. 8, Issue 51, pp. 88630-88644, (2017) (PubMed).
抗原

BAX (BCL2-Associated X Protein (BAX))

别名

BAX (BAX 产品)

别名

BAX-ALPHA antibody, bax-A antibody, xBax antibody, xlbax antibody, BAX antibody, bax antibody, fj16e01 antibody, wu:fc50b10 antibody, wu:fj16e01 antibody, BCL2L4 antibody, zgc:112983 antibody, BCL2 associated X, apoptosis regulator antibody, BCL2-associated X protein L homeolog antibody, BCL2-associated X protein antibody, bcl2-associated X protein, a antibody, bcl2-associated X protein, b antibody, BAX antibody, bax.L antibody, bax antibody, baxa antibody, Bax antibody, baxb antibody

背景

Description: Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM) (PubMed:21458670). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Gene: BAX

分子量

21kDa

基因ID

581

UniProt

Q07812

途径

p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response