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BAX 抗体 (AA 1-100)

Name: BAX 抗体 (AA 1-100)
Brand: antibodies-online
SKU: ABIN3020683
Availability: OutOfStock

BAX 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

CRAMP is reduced in cardiac ischemia/reperfusion (I/R) injury and prevents cardiomyocyte apoptosis. (BAX 抗体 (AA 1-100))

Immunohistochemistry of paraffin-embedded mouse spinal cord using [KO Validated] Bax Rabbit pAb (ABIN3020682, ABIN3020683, ABIN3020684, ABIN1512622 and ABIN6213665) at dilution of 1:100 (40x lens). (BAX 抗体 (AA 1-100))

IHC

Apoptosis related proteins were detected in EOMA cells after treated with DHTS and propranolol. (BAX 抗体 (AA 1-100))

CRAMP reduces cardiac I/R injury in vivo. (BAX 抗体 (AA 1-100))

AS/IV reduces the expression of apoptosis-related proteins by regulating the MAPKs signaling pathway. (BAX 抗体 (AA 1-100))

Western blot analysis of extracts of 293T cells, using Bax antibody (ABIN3020682, ABIN3020683, ABIN3020684, ABIN1512622 and ABIN6213665) at 1:1000 dilution. (BAX 抗体 (AA 1-100))

Western blot analysis of extracts of various cell lines, using Bax antibody (ABIN3020682, ABIN3020683, ABIN3020684, ABIN1512622 and ABIN6213665) at 1:1000 dilution. (BAX 抗体 (AA 1-100))

Western blot analysis of extracts of Mouse brain , using Bax antibody (ABIN3020682, ABIN3020683, ABIN3020684, ABIN1512622 and ABIN6213665) at 1:1000 dilution. (BAX 抗体 (AA 1-100))

Immunofluorescence analysis of HeLa cells using [KO Validated] Bax Rabbit pAb (ABIN3020682, ABIN3020683, ABIN3020684, ABIN1512622 and ABIN6213665) at dilution of 1:50 (40x lens). (BAX 抗体 (AA 1-100))

Immunofluorescence analysis of HepG2 cells using [KO Validated] Bax Rabbit pAb (ABIN3020682, ABIN3020683, ABIN3020684, ABIN1512622 and ABIN6213665) at dilution of 1:50 (40x lens). (BAX 抗体 (AA 1-100))

Immunofluorescence analysis of MCF7 cells using [KO Validated] Bax Rabbit pAb (ABIN3020682, ABIN3020683, ABIN3020684, ABIN1512622 and ABIN6213665) at dilution of 1:50 (40x lens). (BAX 抗体 (AA 1-100))

12 images

(13 references)

产品编号 ABIN3020683

发货至: 中国

Datasheet as PDF

抗原 See all BAX 抗体

BAX (BCL2-Associated X Protein (BAX))
抗原表位
40

32

20

18

15

11

10

10

9

8

8

7

6

6

5

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-100
适用
258

156

143

46

31

27

25

18

17

10

9

5

3

3

3

2

1

1

1

1

1
人
宿主
169

97

4

2
兔
Compatible Secondaries
克隆类型
181

91
多克隆
标记
143

16

13

13

10

7

6

6

6

6

6

6

5

5

5

5

5

1

1

1

1

1

1

1

1

1
This BAX antibody is un-conjugated
应用范围
242

114

73

65

52

52

52

44

42

14

12

8

5

3

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

序列

MDGSGEQPRG GGPTSSEQIM KTGALLLQGF IQDRAGRMGG EAPELALDPV PQDASTKKLS ECLKRIGDEL DSNMELQRMI AAVDTDSPRE VFFRVAADMF

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Bax (NP_620116.1).

亚型

IgG

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BAX 适用: 人, 小鼠, 大鼠, Pig, Cow, 兔, 小鸡, 斑马鱼 WB, ELISA, FACS, IP, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) (N-Term) antibody
BAX 适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, 兔, 犬, 小鸡, 绵羊, 马, 豚鼠, Hamster, 山羊, Avian, Cat, 驴 WB, IF 宿主: 山羊 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) antibody
KO Validated BAX 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) antibody
BAX 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 1-158) antibody
BAX 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibody
BAX 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F5-1B7 unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibody
BAX 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 4H9B11 unconjugated

anti-BCL2-Associated X Protein (BAX) antibody
BAX 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2D8H2 unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibody
BAX 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB0952 unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibody
BAX 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200,IP,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Zhao, Liu, Lin, Huang, He, Zhang, Dong, Wen, Rao, Liao, Shi: "The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1." in: Molecular cancer, Vol. 17, Issue 1, pp. 69, (2019) (PubMed).

Bei, Xu, Lv, Yu, Xu, Che, Das, Tigges, Toxavidis, Ghiran, Shah, Li, Zhang, Das, Xiao: "Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury." in: Basic research in cardiology, Vol. 112, Issue 4, pp. 38, (2018) (PubMed).

Guo, Wang, Mou, Zhao, Yang, Zhu, Pei, Zhu, Wang, Xu, Zeng, Yao: "Pretreatment of Huaiqihuang extractum protects against cisplatin-induced nephrotoxicity." in: Scientific reports, Vol. 8, Issue 1, pp. 7333, (2018) (PubMed).

Li, Zhou, Yang, Li, Zhang, Wang, Jiao: "SGK1 inhibits PM2.5-induced apoptosis and oxidative stress in human lung alveolar epithelial A549 cells." in: Biochemical and biophysical research communications, Vol. 496, Issue 4, pp. 1291-1295, (2018) (PubMed).

Gu, Liu, Li, Xie, Yao, Zhu, Xu, Dai, Zhong, Zhu, Ding, Zhou: "Serum-Derived Extracellular Vesicles Protect Against Acute Myocardial Infarction by Regulating miR-21/PDCD4 Signaling Pathway." in: Frontiers in physiology, Vol. 9, pp. 348, (2018) (PubMed).

Li, Liu, Xie, Gu, Dai, Yao, Zhou: "Serum Exosomes Attenuate H2O2-Induced Apoptosis in Rat H9C2 Cardiomyocytes via ERK1/2." in: Journal of cardiovascular translational research, (2018) (PubMed).

Ding, Wen: "Dandelion root extract protects NCM460 colonic cells and relieves experimental mouse colitis." in: Journal of natural medicines, Vol. 72, Issue 4, pp. 857-866, (2018) (PubMed).

Chen, Cheng, Gao, Zhan, Wang, Qu, Li, Wang, Chen, Meng, Liu, Chen, Chen: "Natural Compound Methyl Protodioscin Suppresses Proliferation and Inhibits Glycolysis in Pancreatic Cancer." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 7343090, (2018) (PubMed).

Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).

Ge, Zhao, Wang, Li, Yu, He, Xue, Zhu, Zhang, Cheng, Jiang, Hu: "iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding." in: Cancer cell, Vol. 32, Issue 5, pp. 561-573.e6, (2017) (PubMed).

Feng, Yu, Liu, Zhang, Cheng, Li, Tan, Luo, Jiang: "KAT5 silencing induces apoptosis of GBC-SD cells through p38MAPK-mediated upregulation of cleaved Casp9." in: International journal of clinical and experimental pathology, Vol. 7, Issue 1, pp. 80-91, (2014) (PubMed).

He, Zhang, Wang, Zhong, Shao, Zhu, Shen: "AURKA suppression induces DU145 apoptosis and sensitizes DU145 to docetaxel treatment." in: American journal of translational research, Vol. 5, Issue 3, pp. 359-67, (2013) (PubMed).

Bao, Lu, Bin, Chang, Meng, Zhou, Guo, Zhao: "Systematic screen with kinases inhibitors reveals kinases play distinct roles in growth of osteoprogenitor cells." in: International journal of clinical and experimental pathology, Vol. 6, Issue 10, pp. 2082-91, (2013) (PubMed).
抗原

BAX (BCL2-Associated X Protein (BAX))

别名

BAX (BAX 产品)

别名

BAX-ALPHA antibody, bax-A antibody, xBax antibody, xlbax antibody, BAX antibody, bax antibody, fj16e01 antibody, wu:fc50b10 antibody, wu:fj16e01 antibody, BCL2L4 antibody, zgc:112983 antibody, BCL2 associated X, apoptosis regulator antibody, BCL2-associated X protein L homeolog antibody, BCL2-associated X protein antibody, bcl2-associated X protein, a antibody, bcl2-associated X protein, b antibody, BAX antibody, bax.L antibody, bax antibody, baxa antibody, Bax antibody, baxb antibody

背景

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.,BCL2L4,BAX,Cancer,Invasion and Metastasis,Signal Transduction,PI3K-Akt Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Bcl 2 family,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Warburg Effect,Neuroscience,Neurodegenerative Diseases,BAX

分子量

4 kDa/12 kDa/15 kDa/18 kDa/19 kDa/21 kDa/24 kDa

基因ID

581

UniProt

Q07812

途径

p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response