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CDC42 抗体 (Internal Region)

CDC42 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6258461
发货至: 中国
  • 抗原 See all CDC42 抗体
    CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
    抗原表位
    • 16
    • 7
    • 7
    • 7
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    • 2
    • 2
    • 1
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    • 1
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    Internal Region
    适用
    • 82
    • 38
    • 37
    • 11
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 77
    • 5
    • 2
    克隆类型
    • 67
    • 15
    多克隆
    标记
    • 38
    • 6
    • 5
    • 3
    • 3
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    • 3
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    • 3
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    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDC42 antibody is un-conjugated
    应用范围
    • 53
    • 27
    • 14
    • 13
    • 13
    • 11
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    Rac1/cdc42 Antibody detects endogenous levels of total Rac1/cdc42.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Rac1/cdc42, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CDC42 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
    别名
    CDC42 (CDC42 产品)
    别名
    CDC42Hs antibody, G25K antibody, AI747189 antibody, AU018915 antibody, cdc42a antibody, wu:fb07d08 antibody, wu:fj62g06 antibody, zgc:63918 antibody, Xcdc42 antibody, cdc42hs antibody, g25k antibody, CDC42 antibody, CG12530 antibody, Cdc42Dm antibody, D-CDC42 antibody, D-Cdc42 antibody, D-cdc42 antibody, DCDC42 antibody, DCdc42 antibody, Dcdc42 antibody, Dm Cdc42 antibody, DmCDC42 antibody, Dmcdc42 antibody, Dmel\\CG12530 antibody, cdc42 antibody, cell division cycle 42 antibody, Cell division control protein 42 homolog antibody, cell division control protein 42 homolog antibody, cell division cycle 42 L homeolog antibody, CG12530 gene product from transcript CG12530-RC antibody, Rho family GTPase antibody, CDC42 antibody, Cdc42 antibody, cdc42 antibody, LOC100636735 antibody, LOC100637699 antibody, LOC100638834 antibody, cdc42.L antibody
    背景

    Description: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration. Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. Facilitates filopodia formation upon DOCK11-activation (By similarity). Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups.

    Gene: CDC42

    分子量
    ?21 kDa
    基因ID
    998
    UniProt
    P60953
    途径
    MAPK Pathway, Microtubule Dynamics, RTK signaling, WNT signaling, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling
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