CDC42 抗体 (Middle Region)
(1 reference)-
- 抗原 See all CDC42 抗体
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
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抗原表位
- AA 121-138, Middle Region
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适用
- 人, 小鼠, 大鼠, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC42 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Cell division control protein 42 homolog(CDC42) detection. Tested with WB, IHC-P in Human,Bovin,Mouse,Rat.
- 序列
- DDPSTIEKLA KNKQKPIT
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Cell division control protein 42 homolog(CDC42) detection. Tested with WB, IHC-P in Human,Bovin,Mouse,Rat.
Gene Name: cell division cycle 42(GTP binding protein, 25 kDa)
Protein Name: Cell division control protein 42 homolog(Cdc42 homolog) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human CDC42(121-138aa DDPSTIEKLAKNKQKPIT), identical to the related mouse and rat sequences.
- 亚型
- IgG
- Top Product
- Discover our top product CDC42 Primary Antibody
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anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 25-191) antibody
CDC42 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal M152 unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 3C3 unconjugated Recombinant Antibody
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-191) antibodyCDC42 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (Internal Region) antibodyCDC42 适用: 人, 小鼠, 大鼠, Cow WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-188) antibodyCDC42 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 2-188) antibodyCDC42 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1 unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Bovine, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in Alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and ..." in: PLoS ONE, Vol. 12, Issue 9, pp. e0185102, (2017) (PubMed).
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: "Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in Alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and ..." in: PLoS ONE, Vol. 12, Issue 9, pp. e0185102, (2017) (PubMed).
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- 抗原
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
- 别名
- CDC42 (CDC42 产品)
- 别名
- CDC42Hs antibody, G25K antibody, AI747189 antibody, AU018915 antibody, cdc42a antibody, wu:fb07d08 antibody, wu:fj62g06 antibody, zgc:63918 antibody, Xcdc42 antibody, cdc42hs antibody, g25k antibody, CDC42 antibody, CG12530 antibody, Cdc42Dm antibody, D-CDC42 antibody, D-Cdc42 antibody, D-cdc42 antibody, DCDC42 antibody, DCdc42 antibody, Dcdc42 antibody, Dm Cdc42 antibody, DmCDC42 antibody, Dmcdc42 antibody, Dmel\\CG12530 antibody, cdc42 antibody, cell division cycle 42 antibody, Cell division control protein 42 homolog antibody, cell division control protein 42 homolog antibody, cell division cycle 42 L homeolog antibody, CG12530 gene product from transcript CG12530-RC antibody, Rho family GTPase antibody, CDC42 antibody, Cdc42 antibody, cdc42 antibody, LOC100636735 antibody, LOC100637699 antibody, LOC100638834 antibody, cdc42.L antibody
- 背景
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Cell division control protein 42 homolog also known as CDC42 is a protein involved in regulation of the cell cycle. In humans, CDC42 is encoded by the CDC42 gene. CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein(N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
Synonyms: CDC 42 antibody|CDC42 antibody|CDC42_HUMAN antibody|CDC42Hs antibody|Cell division control protein 42 homolog antibody|Cell division cycle 42(GTP binding protein 25 kDa) antibody|Cell division cycle 42 antibody|Cell division cycle 42 isoform 1 antibody|Cell division cycle 42 isoform 2 antibody|dJ224A6.1.1(cell division cycle 42(GTP-binding protein, 25kD)) antibody|dJ224A6.1.1 antibody|dJ224A6.1.2(cell division cycle 42(GTP-binding protein, 25kD)) antibody|dJ224A6.1.2 antibody|G25K antibody|G25K GTP binding protein antibody|G25K GTP-binding protein antibody|Growth regulating protein antibody|GTP binding protein 25kD antibody|GTP binding protein 25 kDa antibody|Small GTP binding protein CDC42 antibody - UniProt
- P60953
- 途径
- MAPK Pathway, Microtubule Dynamics, RTK signaling, WNT signaling, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling
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