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GRK2 抗体
ADRBK1
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC (p)
宿主: 兔
Polyclonal
unconjugated
GRK2抗体详情
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抗原
See all GRK2 (ADRBK1) 抗体
GRK2 (ADRBK1)
(Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
适用
All reactivities for GRK2 抗体
人, 小鼠, 大鼠
宿主
All hosts for GRK2 抗体
兔
克隆类型
All clonalities for GRK2 抗体
多克隆
标记
All conjugates for GRK2 抗体
This GRK2 antibody is un-conjugated
应用范围
All applications for GRK2 抗体
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
ADRBK1,Adrenergic beta receptor kinase 1,ARBK1,BARK,BARK1,Beta adrenergic receptor kinase 1,Beta ARK 1,Beta ARK1,Beta-adrenergic receptor kinase 1,Beta-ARK-1,FLJ16718,G protein coupled receptor kinase 2,G-protein coupled receptor kinase 2,GRK2
纯化方法
Affinity purification
免疫原
Synthesized peptide derived from the C-terminal region of human GRK 2
亚型
IgG
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Discover our top product ADRBK1 Primary Antibody
Alternatives
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使用细节
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应用备注
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
限制
仅限研究用
贮存及处理
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浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol pH 7.4.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
GRK2目标详情
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抗原
GRK2 (ADRBK1)
(Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
别名
GRK 2 (ADRBK1 产品 )
别名
Adrbk-1 antibody, Bark-1 antibody, GRK2 antibody, betaARK1 antibody, BARK1 antibody, BETA-ARK1 antibody, GRK-2 antibody, Grk2 antibody, beta-adrenergic receptor kinase 1 antibody, G protein-coupled receptor kinase 2 antibody, Tsp_00497 antibody, grk2 antibody, Grk2 antibody, GRK2 antibody
背景
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
分子量
80kDa
基因ID
156
UniProt
P25098
途径
EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of G-Protein Coupled Receptor Protein Signaling , CXCR4-mediated Signaling Events , G-protein mediated Events , Interaction of EGFR with phospholipase C-gamma , Thromboxane A2 Receptor Signaling
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