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GRK2 抗体

KO Validated ADRBK1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7259288
发货至: 中国
  • 抗原 See all GRK2 (ADRBK1) 抗体
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    适用
    • 98
    • 77
    • 56
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 92
    • 8
    • 2
    • 2
    克隆类型
    • 87
    • 17
    多克隆
    标记
    • 58
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRK2 antibody is un-conjugated
    应用范围
    • 56
    • 45
    • 30
    • 17
    • 14
    • 13
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    This antibody ist KO validated.
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    质量等级
    KO Validated
    免疫原
    Recombinant fusion protein of human ADRBK1 (NP_001610.2).
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    别名
    ADRBK1 (ADRBK1 产品)
    别名
    Adrbk-1 antibody, Bark-1 antibody, GRK2 antibody, betaARK1 antibody, BARK1 antibody, BETA-ARK1 antibody, GRK-2 antibody, Grk2 antibody, beta-adrenergic receptor kinase 1 antibody, G protein-coupled receptor kinase 2 antibody, Tsp_00497 antibody, grk2 antibody, Grk2 antibody, GRK2 antibody
    背景
    The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
    分子量

    Observed_MW: 80 kDa

    Calculated_MW: 79 kDa

    基因ID
    156
    UniProt
    P25098
    途径
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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