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GRK2 抗体

KO Validated ADRBK1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7265504
发货至: 中国
  • 抗原 See all GRK2 (ADRBK1) 抗体
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    适用
    • 98
    • 78
    • 57
    • 8
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    • 2
    • 2
    • 1
    宿主
    • 92
    • 8
    • 2
    • 2
    克隆类型
    • 88
    • 16
    单克隆
    标记
    • 58
    • 7
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    • 4
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    • 1
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    This GRK2 antibody is un-conjugated
    应用范围
    • 56
    • 45
    • 31
    • 17
    • 14
    • 13
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    原理
    [KO Validated] GRK2 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    质量等级
    KO Validated
    免疫原
    A synthesized peptide derived from human GRK2
    亚型
    IgG
    Top Product
    Discover our top product ADRBK1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    别名
    GRK2 (ADRBK1 产品)
    别名
    Adrbk-1 antibody, Bark-1 antibody, GRK2 antibody, betaARK1 antibody, BARK1 antibody, BETA-ARK1 antibody, GRK-2 antibody, Grk2 antibody, beta-adrenergic receptor kinase 1 antibody, G protein-coupled receptor kinase 2 antibody, Tsp_00497 antibody, grk2 antibody, Grk2 antibody, GRK2 antibody
    背景
    The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008],ADRBK1, BARK1, BETA-ARK1,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,G protein signaling_G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Neuroscience,Signal Transduction,GRK2
    分子量
    80kDa
    基因ID
    156
    UniProt
    P25098
    途径
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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