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BAX 抗体

BAX 适用: 人, 小鼠, 大鼠, 兔, 绵羊 WB, ELISA, IHC, IF, FACS, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5700359
发货至: 中国
  • 抗原 See all BAX 抗体
    BAX (BCL2-Associated X Protein (BAX))
    适用
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    人, 小鼠, 大鼠, 兔, 绵羊
    宿主
    • 166
    • 95
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    克隆类型
    • 180
    • 86
    多克隆
    标记
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    This BAX antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)
    免疫原
    BCL2-associated X protein
    亚型
    IgG
    Top Product
    Discover our top product BAX Primary Antibody
  • 应用备注
    WB : 1:1000-1:10000 IP : 1:1000-1:10000 IHC : 1:20-1:200 IF : 1:10-1:100
    说明

    HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00810(BAX antibody) at dilution of 1:1000

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    BAX (BCL2-Associated X Protein (BAX))
    别名
    BAX (BAX 产品)
    别名
    BAX-ALPHA antibody, bax-A antibody, xBax antibody, xlbax antibody, BAX antibody, bax antibody, fj16e01 antibody, wu:fc50b10 antibody, wu:fj16e01 antibody, BCL2L4 antibody, zgc:112983 antibody, BCL2 associated X, apoptosis regulator antibody, BCL2-associated X protein L homeolog antibody, BCL2-associated X protein antibody, bcl2-associated X protein, a antibody, bcl2-associated X protein, b antibody, BAX antibody, bax.L antibody, bax antibody, baxa antibody, Bax antibody, baxb antibody
    背景
    Synonyms:BCL2L4,Apoptosis regulator BAX, BAX Background:BAX, also named as BCL2L4, is a pro-apoptotic member of the Bcl-2 protein family, which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells, but accumulates on the outer mitochondrial membrane upon apoptosis induction(PMID: 9108035). BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane, which leads to the release of cytochrome c from mitochondria(PMID: 21763611). The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis(PMID: 8183579).
    分子量
    21 kDa
    基因ID
    581
    UniProt
    Q07812
    途径
    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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