C-JUN 抗体 (AA 201-250)
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Quick Overview for C-JUN 抗体 (AA 201-250) (ABIN5541526)
抗原
See all C-JUN (JUN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-250
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特异性
- The antibody detects endogenous levels of c-Jun protein (region surrounding Pro233). Species: Human, Mouse, Rat.
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纯化方法
- Affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthetic peptide, corresponding to amino acids 201-250 of Human c-Jun.
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anti-Jun Proto-Oncogene (JUN) (AA 31-331) antibody
JUN 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (AA 1-70) antibodyJUN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人, 小鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5B1 unconjugated
anti-Jun Proto-Oncogene (JUN) (AA 1-70) antibodyJUN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (pThr91) antibodyJUN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (pSer73) antibodyJUN 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (N-Term) antibodyJUN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyKD Validated JUN 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB5760 unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 9F5 unconjugated
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应用备注
- ELISA: 1/10000-1/20000. Western blot : 1/500-1/1000. Immunochemistry on Paraffin Sections : 1/50-1/200.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 95 % pure by SDS-PAGE) Aff - Purified
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- C-JUN (JUN) (Jun Proto-Oncogene (JUN))
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别名
- ap-1,c-jun
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背景
- Genes belonging to the Jun and Fos oncogene families encode nuclear proteins that are found to be associated with a number of transcriptional complexes. The c-Jun protein is a major component of the transcription factor AP-1, originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA- response element (TRE). The Jun proteins form homo- and heterodimers which bind the TRE, while Fos proteins are active only as heterodimers with any of the Jun proteins. Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. An inhibitor of Fos/Jun function, termed IP-1, associates with Fos and Jun and is inactivated upon phosphorylation induced by the cAMP-dependent protein kinase A (PKA).
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UniProt
- P05412
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途径
- MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
抗原
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