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RECQL2 抗体 (AA 787-816)

WRN 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5534828
发货至: 中国
  • 抗原 See all RECQL2 (WRN) 抗体
    RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
    抗原表位
    • 7
    • 7
    • 7
    • 7
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 787-816
    适用
    • 42
    • 2
    • 1
    宿主
    • 35
    • 7
    克隆类型
    • 35
    • 7
    多克隆
    标记
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RECQL2 antibody is un-conjugated
    应用范围
    • 32
    • 21
    • 13
    • 7
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This WRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 787-816 amino acids from the Central region of human WRN.
    亚型
    Ig Fraction
    Top Product
    Discover our top product WRN Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For FACS starting dilution is: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
    别名
    WRN (WRN 产品)
    别名
    RECQ3 antibody, RECQL2 antibody, RECQL3 antibody, xBLM antibody, recq2 antibody, recql2 antibody, recql3 antibody, AI846146 antibody, ffa-1 antibody, xwrn antibody, RGD1564788 antibody, Werner syndrome RecQ like helicase antibody, mediator of RNA polymerase II transcription subunit 34 antibody, Bloom syndrome RecQ like helicase antibody, Werner syndrome, RecQ helicase-like L homeolog antibody, WRN antibody, LOC9327212 antibody, blm antibody, Wrn antibody, wrn.L antibody
    背景
    This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.
    分子量
    162 kDa
    基因ID
    7486
    UniProt
    Q14191
    途径
    DNA Damage Repair
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