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RECQL2 抗体

There is 1 publication for this product available. The 小鼠 单克隆 anti-RECQL2 antibody is suitable to detect RECQL2 in samples from 人. It has been validated for WB, IHC, IF 和 ICC.
产品编号 ABIN2668372
发货至: 中国
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Quick Overview for RECQL2 抗体 (ABIN2668372)

抗原

See all RECQL2 (WRN) 抗体
RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

适用

  • 49
  • 3
  • 2

宿主

  • 34
  • 16
小鼠

克隆类型

  • 32
  • 18
单克隆

标记

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  • 2
  • 2
  • 1
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  • 1
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This RECQL2 antibody is un-conjugated

应用范围

  • 36
  • 20
  • 16
  • 13
  • 9
  • 8
  • 6
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

195C
  • 原理

    WRN antibody (mAb) (Clone 195C)

    纯化方法

    Protein G Chromatography

    免疫原

    This WRN antibody was raised against a recombinant protein corresponding to amino acids 1072 - 1432 of human WRN.

    亚型

    IgG1
  • 应用备注

    ICC/IF: 0.5 μg/mL dilution IHC(P): User optimization required WB: 0.5 - 2 μg/mL dilution

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Opresko, Calvo, von Kobbe: "Role for the Werner syndrome protein in the promotion of tumor cell growth." in: Mechanisms of ageing and development, Vol. 128, Issue 7-8, pp. 423-36, (2007) (PubMed).

  • 抗原

    RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

    别名

    WRN

    背景

    WRN protein is a RECQ helicase that contains 3' to 5' helicase activity and DNA-dependent ATPase activity. WRN takes part in many processes, including DNA replication, recombination, repair, and telomere maintenance. Mutations in the gene encoding WRN cause an autosomal recessive segmental progeria called Werner syndrome (WS). WS patients prematurely develop atrophic skin, thin gray hair, osteoporosis, type II diabetes, cataracts, arteriosclerosis and cancer.

    分子量

    162 kDa

    基因ID

    7486

    NCBI登录号

    NP_000544

    途径

    DNA Damage Repair
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