RECQL2 抗体
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北京 101111
Quick Overview for RECQL2 抗体 (ABIN2668372)
抗原
See all RECQL2 (WRN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- WRN antibody (mAb) (Clone 195C)
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纯化方法
- Protein G Chromatography
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免疫原
- This WRN antibody was raised against a recombinant protein corresponding to amino acids 1072 - 1432 of human WRN.
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亚型
- IgG1
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应用备注
- ICC/IF: 0.5 μg/mL dilution IHC(P): User optimization required WB: 0.5 - 2 μg/mL dilution
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "Role for the Werner syndrome protein in the promotion of tumor cell growth." in: Mechanisms of ageing and development, Vol. 128, Issue 7-8, pp. 423-36, (2007) (PubMed).
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- RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
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别名
- WRN
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背景
- WRN protein is a RECQ helicase that contains 3' to 5' helicase activity and DNA-dependent ATPase activity. WRN takes part in many processes, including DNA replication, recombination, repair, and telomere maintenance. Mutations in the gene encoding WRN cause an autosomal recessive segmental progeria called Werner syndrome (WS). WS patients prematurely develop atrophic skin, thin gray hair, osteoporosis, type II diabetes, cataracts, arteriosclerosis and cancer.
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分子量
- 162 kDa
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基因ID
- 7486
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NCBI登录号
- NP_000544
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途径
- DNA Damage Repair
抗原
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