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RECQL2 抗体 (Middle Region, Thr802)

WRN 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN955584
发货至: 中国
  • 抗原 See all RECQL2 (WRN) 抗体
    RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
    抗原表位
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 794-825, Middle Region, Thr802
    适用
    • 41
    • 2
    • 1
    宿主
    • 34
    • 7
    克隆类型
    • 34
    • 7
    多克隆
    标记
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RECQL2 antibody is un-conjugated
    应用范围
    • 31
    • 21
    • 12
    • 7
    • 6
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects WRN (Center).
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein A column; followed by peptide affinity purification
    免疫原
    KLH conjugated synthetic peptide between 794-825 (T802 amino acids from the Central region of human WRN
    亚型
    Ig Fraction
    Top Product
    Discover our top product WRN Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • 抗原
    RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
    别名
    WRN (WRN 产品)
    别名
    RECQ3 antibody, RECQL2 antibody, RECQL3 antibody, xBLM antibody, recq2 antibody, recql2 antibody, recql3 antibody, AI846146 antibody, ffa-1 antibody, xwrn antibody, RGD1564788 antibody, Werner syndrome RecQ like helicase antibody, mediator of RNA polymerase II transcription subunit 34 antibody, Bloom syndrome RecQ like helicase antibody, Werner syndrome, RecQ helicase-like L homeolog antibody, WRN antibody, LOC9327212 antibody, blm antibody, Wrn antibody, wrn.L antibody
    背景
    This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.Synonyms: DNA helicase, Exonuclease WRN, RECQ3, RECQL2, RecQ protein-like 2, RecQ-like type 3, RecQ3, Werner syndrome ATP-dependent helicase
    基因ID
    7486
    NCBI登录号
    NP_000544
    途径
    DNA Damage Repair
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