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NFATC1 抗体 (AA 589-652)

NFATC1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5519043
发货至: 中国
  • 抗原 See all NFATC1 抗体
    NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
    抗原表位
    • 16
    • 10
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    • 9
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    • 7
    • 7
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    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 589-652
    适用
    • 100
    • 46
    • 24
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 93
    • 6
    • 1
    克隆类型
    • 86
    • 14
    多克隆
    标记
    • 43
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NFATC1 antibody is un-conjugated
    应用范围
    • 53
    • 32
    • 27
    • 16
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    Rabbit IgG polyclonal antibody for NFAT2 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for NFAT2 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
    Gene Name: nuclear factor of activated T-cells 1
    Protein Name: Nuclear factor of activated T-cells, cytoplasmic 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived huamn NFAT2 recombinant protein (Position: Q589-K652).
    亚型
    IgG
    Top Product
    Discover our top product NFATC1 Primary Antibody
  • 应用备注
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
    别名
    NFATC1 (NFATC1 产品)
    别名
    nf-atc antibody, nfat2 antibody, nfatc antibody, si:ch211-198c22.2 antibody, NFATC1 antibody, 2210017P03Rik antibody, AI449492 antibody, AV076380 antibody, NF-ATc antibody, NFAT2 antibody, NFATc antibody, Nfatcb antibody, NF-ATC antibody, NF-ATc1 antibody, NFAT antibody, NFATmac antibody, nuclear factor of activated T-cells 1 antibody, nuclear factor of activated T-cells 1 L homeolog antibody, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 antibody, NFATC1 antibody, nfatc1.L antibody, nfatc1 antibody, Nfatc1 antibody
    背景
    NFATC1(Nuclear factor of activated T-cells, cytoplasmic 1), also known as NFATC or NFAT2, is a protein that in humans is encoded by the NFATC1 gene. And it is also a component of the nuclear factor of activated T cells DNA-binding transcription complex. The NFATC1 gene is mapped on 18q23. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. NFATC1 was not detected in brain, liver, or kidney. NFATC1 is an inducible nuclear component which functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. The solution structure of the binary complex formed between the core DNA-binding domain of human NFATC1 and the 12-bp oligonucleotide duplex containing the ARRE2 DNA site from the IL2 promoter. Nfatc1 was expressed exclusively in mouse hair follicle stem cells, and using gain- and loss-of-function approaches, and Nfatc1 inhibited stem cell activation.

    Synonyms: Nuclear factor of activated T-cells, cytoplasmic 1, NF-ATc1, NFATc1, NFAT transcription complex cytosolic component, NF-ATc, NFATc, NFATC1, NFAT2, NFATC
    基因ID
    4772
    UniProt
    O95644
    途径
    RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway
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