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NFATC1 抗体 (AA 20-300)

NFATC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3022101
发货至: 中国
  • 抗原 See all NFATC1 抗体
    NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
    抗原表位
    • 16
    • 11
    • 10
    • 10
    • 9
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-300
    适用
    • 105
    • 47
    • 25
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    宿主
    • 97
    • 7
    • 1
    克隆类型
    • 90
    • 15
    多克隆
    标记
    • 44
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NFATC1 antibody is un-conjugated
    应用范围
    • 58
    • 35
    • 29
    • 18
    • 13
    • 13
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    VFGRGETLGP APRAGGTMKS AEEEHYGYAS SNVSPALPLP TAHSTLPAPC HNLQTSTPGI IPPADHPSGY GAALDGGPAG YFLSSGHTRP DGAPALESPR IEITSCLGLY HNNNQFFHDV EVEDVLPSSK RSPSTATLSL PSLEAYRDPS CLSPASSLSS RSCNSEASSY ESNYSYPYAS PQTSPWQSPC VSPKTTDPEE GFPRGLGACT LLGSPRHSPS TSPRASVTEE SWLGARSSRP ASPCNKRKYS LNGRQPPYSP HHSPTPSPHG SPRVSVTDDS W
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human NFAT2 (NP_765978.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:3000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Dinesh, Rasool et al.: "Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).

  • 抗原
    NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
    别名
    NFATC1 (NFATC1 产品)
    别名
    nf-atc antibody, nfat2 antibody, nfatc antibody, si:ch211-198c22.2 antibody, NFATC1 antibody, 2210017P03Rik antibody, AI449492 antibody, AV076380 antibody, NF-ATc antibody, NFAT2 antibody, NFATc antibody, Nfatcb antibody, NF-ATC antibody, NF-ATc1 antibody, NFAT antibody, NFATmac antibody, nuclear factor of activated T-cells 1 antibody, nuclear factor of activated T-cells 1 L homeolog antibody, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 antibody, NFATC1 antibody, nfatc1.L antibody, nfatc1 antibody, Nfatc1 antibody
    背景
    The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.,NF-ATC,NF-ATc1.2,NFAT2,NFATc,NFATC1,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-JNK Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Cardiovascular,Heart,Cardiogenesis,NFATC1
    分子量
    38 kDa/74- 88 kDa/100-101 kDa
    基因ID
    4772
    UniProt
    O95644
    途径
    RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway
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