DIO3 抗体 (Middle Region)
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- 抗原 See all DIO3 抗体
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DIO3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EVELNSEGEE VPPDDPPICV SDDNRLCTLA SLKAVWHGQK LDFFKQAHEG
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human DIO3
- Top Product
- Discover our top product DIO3 Primary Antibody
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anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 37-169) antibody
DIO3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 51-150) antibodyDIO3 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 250-278), (C-Term) antibodyDIO3 适用: 人, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal RB24089 unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 250-300) antibodyDIO3 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (Internal Region) antibodyDIO3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 50-115) antibodyDIO3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (Internal Region) antibodyDIO3 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 70-170) antibodyDIO3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 250-278), (C-Term) antibodyDIO3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 249-278), (C-Term) antibodyDIO3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
- 别名
- DIO3 (DIO3 产品)
- 别名
- 5DIII antibody, DIOIII antibody, txdi3 antibody, dioiii antibody, XL-15 antibody, itdi3 antibody, D3 antibody, TXDI3 antibody, iodothyronine deiodinase 3 antibody, deiodinase, iodothyronine, type 3 antibody, deiodinase, iodothyronine, type III antibody, deiodinase, iodothyronine type III antibody, deiodinase, iodothyronine, type 3 L homeolog antibody, DIO3 antibody, dio3 antibody, Dio3 antibody, dio3.L antibody
- 背景
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The protein encoded by this intronless gene belongs to the iodothyronine deiodinase family. It catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. This enzyme is highly expressed in the pregnant uterus, placenta, fetal and neonatal tissues, suggesting that it plays an essential role in the regulation of thyroid hormone inactivation during embryological development. This protein contains a selenocysteine (Sec) residue, which is essential for efficient enzyme activity. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.
Alias Symbols: D3, 5DIII, TXDI3, DIOIII,
Protein Size: 278 - 基因ID
- 1735
- NCBI登录号
- NM_001362, NP_001353
- UniProt
- P55073
- 途径
- Hormone Activity
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