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- 抗原 See all DIO3 抗体
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
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抗原表位
- AA 70-170
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DIO3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- HFLGRRRRGQ PEPEVELNSE GEEVPPDDPP ICVSDDNRLC TLASLKAVWH GQKLDFFKQA HEGGPAPNSE VVLPDGFQSQ HILDYAQGNR PLVLNFGSCT U
- 交叉反应
- 人
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 70-170 of human DIO3 (NP_001353.4).
- 亚型
- IgG
- Top Product
- Discover our top product DIO3 Primary Antibody
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anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 37-169) antibody
DIO3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 51-150) antibodyDIO3 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 250-278), (C-Term) antibodyDIO3 适用: 人, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal RB24089 unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 250-300) antibodyDIO3 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (Internal Region) antibodyDIO3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 50-115) antibodyDIO3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (Internal Region) antibodyDIO3 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 250-278), (C-Term) antibodyDIO3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 249-278), (C-Term) antibodyDIO3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
- 别名
- DIO3 (DIO3 产品)
- 别名
- 5DIII antibody, DIOIII antibody, txdi3 antibody, dioiii antibody, XL-15 antibody, itdi3 antibody, D3 antibody, TXDI3 antibody, iodothyronine deiodinase 3 antibody, deiodinase, iodothyronine, type 3 antibody, deiodinase, iodothyronine, type III antibody, deiodinase, iodothyronine type III antibody, deiodinase, iodothyronine, type 3 L homeolog antibody, DIO3 antibody, dio3 antibody, Dio3 antibody, dio3.L antibody
- 背景
- The protein encoded by this intronless gene belongs to the iodothyronine deiodinase family. It catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. This enzyme is highly expressed in pregnant uterus, placenta, fetal and neonatal tissues, and thought to prevent premature exposure of developing fetal tissues to adult levels of thyroid hormones. It regulates circulating fetal thyroid hormone concentrations, and thus plays a critical role in mammalian development. Knockout mice lacking this gene exhibit abnormalities related to development and reproduction, and increased activity of this enzyme in infants with hemangiomas causes severe hypothyroidism. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.,DIO3,5DIII,D3,DIOIII,TXDI3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,DIO3
- 分子量
- 33 kDa
- 基因ID
- 1735
- UniProt
- P55073
- 途径
- Hormone Activity
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