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DIO3 抗体

(Deiodinase, Iodothyronine, Type III (DIO3))
The protein encoded by this intronless gene belongs to the iodothyronine deiodinase family. It catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. This enzyme is highly expressed in the pregnant uterus, placenta, fetal and neonatal tissues, suggesting that it plays an essential role in the regulation of thyroid hormone inactivation during embryological development. This protein contains a selenocysteine (Sec) residue, which is essential for efficient enzyme activity. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008].

Active filters:

  • 抗原: DIO3
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7436198
DIO3 抗体 (AA 37-169) DIO3 · Primary Antibody 大鼠 兔 Polyclonal
  • WB (Western Blotting: 有验证图片)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • 100 μL
  • 1 mL
  • 20 μL
  • 200 μL
发货至: 中国
ABIN653482
DIO3 抗体 (C-Term) DIO3 · Primary Antibody 人, 大鼠 兔 Polyclonal 克隆位点 RB24089
  • WB (Western Blotting: 有验证图片)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
  • IHC (Immunohistochemistry: 所列应用)
  • 400 μL
  • 80 μL
发货至: 中国
ABIN750883
DIO3 抗体 (AA 51-150) DIO3 · Primary Antibody 人 兔 Polyclonal
  • ELISA (ELISA: 有验证图片)
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN6139627
DIO3 抗体 (AA 70-170) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 有验证图片)
  • 100 μL
  • 1 mL
  • 20 μL
  • 500 μL
发货至: 中国
ABIN7172188
DIO3 抗体 (AA 50-115) DIO3 · Primary Antibody 人 兔 Polyclonal
  • IF (Immunofluorescence: 有验证图片)
  • ELISA (ELISA: 所列应用)
  • 100 μg
  • 50 μg
发货至: 中国
ABIN3184310
DIO3 抗体 (Internal Region) DIO3 · Primary Antibody 人, 大鼠, 小鼠 兔 Polyclonal
  • WB (Western Blotting: 有验证图片)
  • ELISA (ELISA: 所列应用)
  • 100 μL
  • 50 μL
  • 200 μL
发货至: 中国
ABIN750885
DIO3 抗体 (AA 51-150) (Biotin) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN750892
DIO3 抗体 (AA 51-150) (HRP) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • 100 μL
发货至: 中国
ABIN2812390
DIO3 抗体 (AbBy Fluor® 594) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
  • 100 μL
发货至: 中国
ABIN894005
DIO3 抗体 (AbBy Fluor® 555) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN894008
DIO3 抗体 (AbBy Fluor® 350) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN5001269
DIO3 抗体 (AbBy Fluor® 680) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN894006
DIO3 抗体 (AbBy Fluor® 647) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN894004
DIO3 抗体 (AbBy Fluor® 488) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN750889
DIO3 抗体 (Cy7) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN750886
DIO3 抗体 (Cy3) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN750887
DIO3 抗体 (Cy5) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN750890
DIO3 抗体 (FITC) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN5001270
DIO3 抗体 (AbBy Fluor® 750) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN750888
DIO3 抗体 (Cy5.5) DIO3 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
Primary Antibody
  • WB (Western Blotting: 有验证图片)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
适用
大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 37-169
产品编号 ABIN7436198
100 μL (More quantities available)
发货至: 中国
获取报价
Primary Antibody
  • WB (Western Blotting: 有验证图片)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
  • IHC (Immunohistochemistry: 所列应用)
适用
人, 大鼠
宿主
兔
克隆形成能力
Polyclonal
克隆
RB24089
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 250-278, C-Term
产品编号 ABIN653482
400 μL (More quantities available)
发货至: 中国
获取报价
Primary Antibody
  • ELISA (ELISA: 有验证图片)
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 51-150
产品编号 ABIN750883
Primary Antibody
  • WB (Western Blotting: 有验证图片)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 70-170
产品编号 ABIN6139627
100 μL (More quantities available)
发货至: 中国
获取报价
Primary Antibody
  • IF (Immunofluorescence: 有验证图片)
  • ELISA (ELISA: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 50-115
产品编号 ABIN7172188
100 μg (More quantities available)
发货至: 中国
获取报价
Primary Antibody
  • WB (Western Blotting: 有验证图片)
  • ELISA (ELISA: 所列应用)
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
Internal Region
产品编号 ABIN3184310
100 μL (More quantities available)
发货至: 中国
获取报价
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Biotin
抗体亚型
IgG
抗原表位
AA 51-150
产品编号 ABIN750885
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
HRP
抗体亚型
IgG
抗原表位
AA 51-150
产品编号 ABIN750892
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 594
抗体亚型
IgG
产品编号 ABIN2812390
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 555
抗体亚型
IgG
产品编号 ABIN894005
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 350
抗体亚型
IgG
产品编号 ABIN894008
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 680
抗体亚型
IgG
产品编号 ABIN5001269
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 647
抗体亚型
IgG
产品编号 ABIN894006
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 488
抗体亚型
IgG
产品编号 ABIN894004
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Cy7
抗体亚型
IgG
产品编号 ABIN750889
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Cy3
抗体亚型
IgG
产品编号 ABIN750886
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Cy5
抗体亚型
IgG
产品编号 ABIN750887
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
FITC
抗体亚型
IgG
产品编号 ABIN750890
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
AbBy Fluor® 750
抗体亚型
IgG
产品编号 ABIN5001270
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Cy5.5
抗体亚型
IgG
产品编号 ABIN750888

Latest Publications for our DIO3 抗体

Calonne, Isacco, Miles-Chan, Arsenijevic, Montani, Guillet, Boirie, Dulloo: "Reduced Skeletal Muscle Protein Turnover and Thyroid Hormone Metabolism in Adaptive Thermogenesis That Facilitates Body Fat Recovery During Weight Regain." in: Frontiers in endocrinology, Vol. 10, pp. 119, (2019) (PubMed).

Benedetti, Lavecchia, Locatelli, Brizi, Corna, Todeschini, Novelli, Benigni, Zoja, Remuzzi, Xinaris: "Alteration of thyroid hormone signaling triggers the diabetes-induced pathological growth, remodeling, and dedifferentiation of podocytes." in: JCI insight, Vol. 4, Issue 18, (2019) (PubMed).

Pörings, Lowin, Dufner, Grifka, Straub: "A thyroid hormone network exists in synovial fibroblasts of rheumatoid arthritis and osteoarthritis patients." in: Scientific reports, Vol. 9, Issue 1, pp. 13235, (2019) (PubMed).

Yamauchi, Sakane, Yamashita, Hirota, Ueda, Kanai, Yamashita, Kondo, Fujii, Taura, Sone, Yasoda, Inagaki: "Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans." in: Endocrine, Vol. 59, Issue 2, pp. 353-363, (2018) (PubMed).

De Andrade, Neff, Strosova, Arsenijevic, Patthey-Vuadens, Scapozza, Montani, Ruegg, Dulloo, Dorchies: "Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding." in: Frontiers in physiology, Vol. 6, pp. 254, (2015) (PubMed).

Maynard, Marino-Enriquez, Fletcher, Dorfman, Raut, Yassa, Guo, Wang, Dorfman, Feldman, Frates, Song, Jugo, Taguchi, Hershman, Larsen, Huang: "Thyroid hormone inactivation in gastrointestinal stromal tumors." in: The New England journal of medicine, Vol. 370, Issue 14, pp. 1327-34, (2014) (PubMed).

Castroneves, Jugo, Maynard, Lee, Wassner, Dorfman, Bronson, Ukomadu, Agoston, Ding, Luongo, Guo, Song, Demchev, Lee, Feldman, Vella, Peake, Hartigan, Kellogg, Desai, Salvatore, Dentice, Huang: "Mice with hepatocyte-specific deficiency of type 3 deiodinase have intact liver regeneration and accelerated recovery from nonthyroidal illness after toxin-induced hepatonecrosis." in: Endocrinology, Vol. 155, Issue 10, pp. 4061-8, (2014) (PubMed).

Medina, Fonesca, Molina, Fachado, Castillo, Dong, Soares, Hernández, Caicedo, Bianco: "Maternal inheritance of an inactive type III deiodinase gene allele affects mouse pancreatic β-cells and disrupts glucose homeostasis." in: Endocrinology, Vol. 155, Issue 8, pp. 3160-71, (2014) (PubMed).

Dudek, Suter, Darras, Marczylo, Gant: "Decreased translation of Dio3 mRNA is associated with drug-induced hepatotoxicity." in: The Biochemical journal, Vol. 453, Issue 1, pp. 71-82, (2013) (PubMed).

Vose, Vinukonda, Jo, Miry, Diamond, Korumilli, Arshad, Zia, Hu, Kayton, La Gamma, Bansal, Bianco, Ballabh: "Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 44, pp. 17232-46, (2013) (PubMed).

Aliases for DIO3 抗体

iodothyronine deiodinase 3 (DIO3) 抗体
deiodinase, iodothyronine, type 3 (dio3) 抗体
deiodinase, iodothyronine, type III (dio3) 抗体
deiodinase, iodothyronine type III (Dio3) 抗体
deiodinase, iodothyronine, type 3 L homeolog (dio3.L) 抗体
iodothyronine deiodinase 3 (Dio3) 抗体
5DIII 抗体
D3 抗体
DIOIII 抗体
dioiii 抗体
itdi3 抗体
txdi3 抗体
TXDI3 抗体
XL-15 抗体
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