DISP1 抗体
(Dispatched Homolog 1 (DISP1))
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008].
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Latest Publications for our DISP1 抗体
: "Evidence for a role of vertebrate Disp1 in long-range Shh signaling." in: Development (Cambridge, England), Vol. 137, Issue 1, pp. 133-40, (2009) (PubMed).
: "Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells." in: Cell, Vol. 99, Issue 7, pp. 803-15, (2000) (PubMed).
: "Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells." in: Cell, Vol. 99, Issue 7, pp. 803-15, (2000) (PubMed).
Aliases for DISP1 抗体
dispatched (CpipJ_CPIJ008642) 抗体dispatched RND transporter family member 1 (DISP1) 抗体
dispatched RND transporter family member 1 (Disp1) 抗体
dispatched homolog 1 (Drosophila) (disp1) 抗体
1190008H24Rik 抗体
con 抗体
DISP1 抗体
DISPA 抗体
DispA 抗体
zgc:111866 抗体
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