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DIO3 抗体 (AA 51-150)

DIO3 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN750883
发货至: 中国
  • 抗原 See all DIO3 抗体
    DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
    抗原表位
    • 10
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    适用
    • 38
    • 25
    • 18
    宿主
    • 48
    • 1
    克隆类型
    • 48
    • 1
    多克隆
    标记
    • 18
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DIO3 antibody is un-conjugated
    应用范围
    • 39
    • 24
    • 15
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Dio3
    亚型
    IgG
    Top Product
    Discover our top product DIO3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
    别名
    Dio3 (DIO3 产品)
    别名
    5DIII antibody, DIOIII antibody, txdi3 antibody, dioiii antibody, XL-15 antibody, itdi3 antibody, D3 antibody, TXDI3 antibody, iodothyronine deiodinase 3 antibody, deiodinase, iodothyronine, type 3 antibody, deiodinase, iodothyronine, type III antibody, deiodinase, iodothyronine type III antibody, deiodinase, iodothyronine, type 3 L homeolog antibody, DIO3 antibody, dio3 antibody, Dio3 antibody, dio3.L antibody
    背景

    Synonyms: Type 3 DI, D3, 5DIII, Deiodinase iodothyronine type 3, Deiodinase iodothyronine type III, Dio 3, DIOIII, MGC124117, MGC124118, TXDI3, Type III 5' deiodinase, Type III iodothyronine deiodinase, IOD3_HUMAN.

    Background: Dio3 belongs to the iodothyronine deiodinase family. It has an essential role for regulation of thyroid hormone inactivation during embryological development in that it catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. Dio3 may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones and has been linked to the development of consumptive hypothyroidism in both infants and adults.

    基因ID
    1735
    途径
    Hormone Activity
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