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- 抗原 See all DIO3 抗体
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
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抗原表位
- AA 250-278, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DIO3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This DIO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-278 amino acids from the C-terminal region of human DIO3.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product DIO3 Primary Antibody
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anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 37-169) antibody
DIO3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 51-150) antibodyDIO3 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 250-278), (C-Term) antibodyDIO3 适用: 人, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal RB24089 unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 250-300) antibodyDIO3 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (Internal Region) antibodyDIO3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 50-115) antibodyDIO3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (Internal Region) antibodyDIO3 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 70-170) antibodyDIO3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type III (DIO3) (AA 249-278), (C-Term) antibodyDIO3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
- 别名
- DIO3 (DIO3 产品)
- 别名
- 5DIII antibody, DIOIII antibody, txdi3 antibody, dioiii antibody, XL-15 antibody, itdi3 antibody, D3 antibody, TXDI3 antibody, iodothyronine deiodinase 3 antibody, deiodinase, iodothyronine, type 3 antibody, deiodinase, iodothyronine, type III antibody, deiodinase, iodothyronine type III antibody, deiodinase, iodothyronine, type 3 L homeolog antibody, DIO3 antibody, dio3 antibody, Dio3 antibody, dio3.L antibody
- 背景
- DIO3 belongs to the iodothyronine deiodinase family. It catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. This enzyme is highly expressed in the pregnant uterus, placenta, fetal and neonatal tissues, suggesting that it plays an essential role in the regulation of thyroid hormone inactivation during embryological development. This protein contains a selenocysteine (Sec) residue, which is essential for efficient enzyme activity. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.
- 分子量
- 34 kDa
- 基因ID
- 1735
- UniProt
- P55073
- 途径
- Hormone Activity
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