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IRAK4 抗体 (pThr345)

IRAK4 适用: 人, 小鼠, Cow, 犬 WB, ELISA, IHC, IP, DB 宿主: 小鼠 Monoclonal A8A8 unconjugated
产品编号 ABIN534253
发货至: 中国
  • 抗原 See all IRAK4 抗体
    IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
    抗原表位
    • 36
    • 16
    • 15
    • 11
    • 8
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr345
    适用
    • 115
    • 66
    • 27
    • 15
    • 14
    • 12
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, Cow, 犬
    宿主
    • 110
    • 10
    • 1
    小鼠
    克隆类型
    • 108
    • 13
    单克隆
    标记
    • 53
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This IRAK4 antibody is un-conjugated
    应用范围
    • 112
    • 51
    • 37
    • 26
    • 18
    • 16
    • 14
    • 10
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Dot Blot (DB)
    原理
    Mouse monoclonal antibody raised against synthetic phosphopeptide of IRAK4.
    序列
    VMTSR
    特异性
    This antibody recognizes IRAK4 (phospho T345) with a phosphorylated site at Threonine 345. It does not cross-react with non-phosphospecific peptide.
    交叉反应
    Cow, 犬, 人, 小鼠
    产品特性
    Antibody Reactive Against Synthetic Peptide.
    免疫原
    Synthetic phosphopeptide corresponding to residues surrounding T345 of human IRAK4.
    克隆位点
    A8A8
    亚型
    IgG1
    Top Product
    Discover our top product IRAK4 Primary Antibody
  • 应用备注
    Western Blot (0.1-1 μg/mL)
    ELISA (0.01-0.1 μg/mL)
    Immunoprecipitation (2-5 μg/mL)
    Immunohistochemistry (2-5 μg/mL)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In TBS, pH 7.2 (BSA, 10 % Proclin300)
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Lehmann, Krüger, Park, Derkow, Rosenberger, Baumgart, Trimbuch, Eom, Hinz, Kaul, Habbel, Kälin, Franzoni, Rybak, Nguyen, Veh, Ninnemann, Peters, Nitsch, Heppner, Golenbock, Schott, Ploegh, Wulczyn et al.: "An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. ..." in: Nature neuroscience, Vol. 15, Issue 6, pp. 827-35, (2012) (PubMed).

    Srivastava, Geng, Liu, Zheng, Li, Joseph, McKenna, Bansal, Ochoa, Davila: "Augmentation of therapeutic responses in melanoma by inhibition of IRAK-1,-4." in: Cancer research, Vol. 72, Issue 23, pp. 6209-16, (2012) (PubMed).

    Li, Strelow, Fontana, Wesche: "IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 8, pp. 5567-72, (2002) (PubMed).

  • 抗原
    IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
    别名
    IRAK4 (IRAK4 产品)
    别名
    zgc:55553 antibody, IRAK4 antibody, ipd1 antibody, irak-4 antibody, ny-ran-64 antibody, ny-ren-64 antibody, ren64 antibody, irak4 antibody, IPD1 antibody, IRAK-4 antibody, NY-REN-64 antibody, REN64 antibody, 8430405M07Rik antibody, 9330209D03Rik antibody, interleukin 1 receptor associated kinase 4 antibody, interleukin-1 receptor-associated kinase 4 antibody, IRAK4 antibody, irak4 antibody, Irak4 antibody
    基因ID
    51135
    途径
    NF-kappaB Signaling, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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