IRAK4 抗体 (pThr345)
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- 抗原 See all IRAK4 抗体
- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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抗原表位
- pThr345
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适用
- 人, 小鼠, Cow, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IRAK4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Dot Blot (DB)
- 原理
- Mouse monoclonal antibody raised against synthetic phosphopeptide of IRAK4.
- 序列
- VMTSR
- 特异性
- This antibody recognizes IRAK4 (phospho T345) with a phosphorylated site at Threonine 345. It does not cross-react with non-phosphospecific peptide.
- 交叉反应
- Cow, 犬, 人, 小鼠
- 产品特性
- Antibody Reactive Against Synthetic Peptide.
- 免疫原
- Synthetic phosphopeptide corresponding to residues surrounding T345 of human IRAK4.
- 克隆位点
- A8A8
- 亚型
- IgG1
- Top Product
- Discover our top product IRAK4 Primary Antibody
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- 应用备注
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Western Blot (0.1-1 μg/mL)
ELISA (0.01-0.1 μg/mL)
Immunoprecipitation (2-5 μg/mL)
Immunohistochemistry (2-5 μg/mL)
The optimal working dilution should be determined by the end user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In TBS, pH 7.2 (BSA, 10 % Proclin300)
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
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Store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.
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An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. ..." in: Nature neuroscience, Vol. 15, Issue 6, pp. 827-35, (2012) (PubMed).
: "Augmentation of therapeutic responses in melanoma by inhibition of IRAK-1,-4." in: Cancer research, Vol. 72, Issue 23, pp. 6209-16, (2012) (PubMed).
: "IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 8, pp. 5567-72, (2002) (PubMed).
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An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. ..." in: Nature neuroscience, Vol. 15, Issue 6, pp. 827-35, (2012) (PubMed).
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- 抗原
- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
- 别名
- IRAK4 (IRAK4 产品)
- 别名
- zgc:55553 antibody, IRAK4 antibody, ipd1 antibody, irak-4 antibody, ny-ran-64 antibody, ny-ren-64 antibody, ren64 antibody, irak4 antibody, IPD1 antibody, IRAK-4 antibody, NY-REN-64 antibody, REN64 antibody, 8430405M07Rik antibody, 9330209D03Rik antibody, interleukin 1 receptor associated kinase 4 antibody, interleukin-1 receptor-associated kinase 4 antibody, IRAK4 antibody, irak4 antibody, Irak4 antibody
- 基因ID
- 51135
- 途径
- NF-kappaB Signaling, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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