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PTPN11 抗体 (C-Term)

Name: PTPN11 抗体 (C-Term)
SKU: ABIN500708
Availability: OutOfStock

PTPN11 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of SHP2 in mouse skeletal muscle tissue lysate with this product at (A) 0. (PTPN11 抗体 (C-Term))

1 image

产品编号 ABIN500708

发货至: 中国

Datasheet as PDF

抗原 See all PTPN11 抗体

PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
抗原表位
32

25

15

15

8

7

7

6

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
153

115

104

10

10

9

8

8

8

7

5

5

4

3

1
人, 小鼠, 大鼠
宿主
168

14

2

1
兔
Compatible Secondaries
克隆类型
148

37
多克隆
标记
87

12

9

9

9

9

9

9

7

5

3

3

2

2

2

2

2

2

2
This PTPN11 antibody is un-conjugated
应用范围
120

50

42

27

26

26

20

16

14

7

6

2

2

1
Western Blotting (WB), Enzyme Immunoassay (EIA)

特异性

This antibody detects PTPN11 / SHP-2 at C-term.

交叉反应（详细）

Species reactivity (tested):Human, mouse, rat

纯化方法

Peptide affinity chromatography

免疫原

SHP2 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human SHP2.

亚型

IgG

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Verified PTPN11 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) antibody
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anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibody
KO Validated PTPN11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 526-551) antibody
PTPN11 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21493 unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) antibody
PTPN11 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 1-460) antibody
PTPN11 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibody
PTPN11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr580) antibody
PTPN11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA. Western blot: 0.5 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
缓冲液

PBS containing 0.02 % sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
抗原

PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

别名

PTPN11 / PTP2C (PTPN11 产品)

别名

BPTP3 antibody, CFC antibody, NS1 antibody, PTP-1D antibody, PTP2C antibody, SH-PTP2 antibody, SH-PTP3 antibody, SHP2 antibody, 2700084A17Rik antibody, AW536184 antibody, PTP1D antibody, SAP-2 antibody, SHP-2 antibody, Shp2 antibody, Syp antibody, SYP antibody, bptp3 antibody, cfc antibody, ns1 antibody, ptp-2 antibody, ptp2c antibody, ptpn11 antibody, ptpn11-a antibody, ptpn11-b antibody, shp-2 antibody, shp2 antibody, fa14b09 antibody, wu:fa14b09 antibody, wu:fi24f03 antibody, zgc:55388 antibody, zgc:63553 antibody, protein tyrosine phosphatase, non-receptor type 11 antibody, protein tyrosine phosphatase, non-receptor type 11 S homeolog antibody, protein tyrosine phosphatase, non-receptor type 11, a antibody, protein tyrosine phosphatase, non-receptor type 11, b antibody, PTPN11 antibody, Ptpn11 antibody, ptpn11.S antibody, ptpn11a antibody, ptpn11b antibody

物质类

Viral Protein

背景

Src homology-2 domain containing protein (SHP2) is a member of the protein tyrosine phosphatase (PTP) family, a protein family that contains signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. SHP2 contains two tandem Src homology-2 (SH2) domains, which function as phosphotyrosine binding domains either directly or through scaffolding intermediates such as the insulin-receptor substrate 1 (IRS-1). These SH2 domains mediate the interaction of SHP2 with its substrates, allowing SHP2 to dephosphorylate proteins that inhibit signaling kinases such as ERK1 and AKT. SHP2 is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Recent experiments have shown SHP2 plays a significant role in hepatoprotection and liver regeneration.Synonyms: PTP-1D, PTP-2C, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, SH-PTP2, SH-PTP3, SHP-2, SHPTP2, Shp2, Tyrosine-protein phosphatase non-receptor type 11

基因ID

5781

NCBI登录号

NP_002825

UniProt

Q06124

途径

JAK/STAT Signaling, RTK signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect