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- 抗原 See all NR3C2 抗体
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR3C2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Antigen affinity
- 免疫原
- Amino acids HALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK of the human protein were used as the immunogen for the MR antibody. This sequence is common to isoforms 1, 3 and 4.
- 亚型
- IgG
- Top Product
- Discover our top product NR3C2 Primary Antibody
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anti-Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) (C-Term) antibody
NR3C2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) antibodyNR3C2 适用: 人, 大鼠, 兔, 小鸡 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal H10E4C9F unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) (AA 601-700) antibodyNR3C2 适用: 人, 大鼠, 小鼠, 犬 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) (AA 739-984) antibodyNR3C2 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) antibodyNR3C2 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) antibodyMicroarray verified NR3C2 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB719560 unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) antibodyMicroarray verified NR3C2 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB252256 unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) (AA 1-110) antibodyNR3C2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) (AA 651-700) antibodyNR3C2 适用: 人, 马, Cow, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) (AA 950-984), (C-Term) antibodyNR3C2 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal dilution of the MR antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the MR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
- 别名
- Mineralocorticoid Receptor / MR (NR3C2 产品)
- 别名
- mr antibody, si:ch211-189l17.1 antibody, LOC100302443 antibody, NR3C2 antibody, LOC443144 antibody, MLR antibody, MR antibody, MCR antibody, NR3C2VIT antibody, Mlr antibody, mlr antibody, nuclear receptor subfamily 3, group C, member 2 antibody, nuclear receptor subfamily 3 group C member 2 antibody, mineralocorticoid receptor antibody, nuclear receptor subfamily 3 group C member 2 L homeolog antibody, nr3c2 antibody, NR3C2 antibody, LOC443144 antibody, Nr3c2 antibody, nr3c2.L antibody
- 背景
- NR3C2 (nuclear receptor subfamily 3, group C, member 2), also known as MR (mineralocorticoid receptor), is a protein that in humans is encoded by the NR3C2 gene that is located on chromosome 4q31.1-31.2. It belongs to the nuclear receptor family where the ligand diffuses into cells, interacts with the receptor and results in a signal transduction affecting specific gene expression in the nucleus. This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
- UniProt
- P08235
- 途径
- ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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