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COL1A1 抗体 (C-Term)

Name: COL1A1 抗体 (C-Term)
SKU: ABIN4886543
Availability: OutOfStock

COL1A1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Collagen I was detected in paraffin-embedded sections of human lung cancer tissues using rabbit anti- Collagen I Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. (COL1A1 抗体 (C-Term))

IHC

Western blot analysis of Collagen I expression in MCF-7 whole cell lysates ( Lane 1). (COL1A1 抗体 (C-Term))

2 images

(46 references)

产品编号 ABIN4886543

发货至: 中国

Datasheet as PDF

抗原 See all COL1A1 抗体

COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
抗原表位
13

9

6

4

4

4

3

2

2

2

2

1

1

1

1

1

1

1
AA 1194-1218, C-Term
适用
58

30

25

12

5

4

4

3

2

2

2

2

1

1

1

1
人
宿主
67

12
兔
Compatible Secondaries
克隆类型
58

21
多克隆
标记
42

9

7

5

2

2

2

2

2

2

2

2
This COL1A1 antibody is un-conjugated
应用范围
52

36

34

11

10

9

7

4

3

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Collagen alpha-1(I) chain(COL1A1) detection. Tested with WB, IHC-P in Human.

序列

AGFDFSFLPQ PPQEKAHDGG RYYRA

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Collagen alpha-1(I) chain(COL1A1) detection. Tested with WB, IHC-P in Human.
Gene Name: collagen, type I, alpha 1
Protein Name: Collagen alpha-1(I) chain

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Collagen I (1194-1218aa AGFDFSFLPQPPQEKAHDGGRYYRA), different from the related mouse and rat sequences by four amino acids.

亚型

IgG

Top Product

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anti-Collagen, Type I, alpha 1 (COL1A1) (AA 1192-1207), (C-Term) antibody
COL1A1 适用: 人, 大鼠, 小鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Collagen, Type I, alpha 1 (COL1A1) (AA 253-471) antibody
COL1A1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Collagen, Type I, alpha 1 (COL1A1) (AA 1225-1453) antibody
COL1A1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Collagen, Type I, alpha 1 (COL1A1) (AA 1218-1440) antibody
COL1A1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated

anti-Collagen, Type I, alpha 1 (COL1A1) (AA 253-471) antibody
COL1A1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated

anti-Collagen, Type I, alpha 1 (COL1A1) antibody
COL1A1 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Collagen, Type I, alpha 1 (COL1A1) (AA 100-200) antibody
COL1A1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Collagen, Type I, alpha 1 (COL1A1) (AA 1021-1108) antibody
COL1A1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G3 unconjugated

anti-Collagen, Type I, alpha 1 (COL1A1) (AA 1219-1464) antibody
COL1A1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7B1G12 unconjugated

anti-Collagen, Type I, alpha 1 (COL1A1) (AA 521-680) antibody
COL1A1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Luo, Li, Liu, Jian, Zou, Zhao, Le, Chen, Gao, He: "Adiponectin Is Involved in Connective Tissue Growth Factor-Induced Proliferation, Migration and Overproduction of the Extracellular Matrix in Keloid Fibroblasts." in: International journal of molecular sciences, Vol. 18, Issue 5, (2018) (PubMed).

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Jiang, Zhong, Zheng, Zhao: "Nano-hydroxyapatite/collagen film as a favorable substrate to maintain the phenotype and promote the growth of chondrocytes cultured in vitro." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 2150-2158, (2018) (PubMed).

Zhang, Ju, Nie, Song, Xu, Gao: "Adenovirus‑mediated knockdown of activin A receptor type 2A attenuates immune‑induced hepatic fibrosis in mice and inhibits interleukin‑17‑induced activation of primary hepatic stellate cells." in: International journal of molecular medicine, Vol. 42, Issue 1, pp. 279-289, (2018) (PubMed).

Zhao, Wang, Wang, Hong, Miao, Liao, Zhou, Liu: "An essential role for Wnt/β-catenin signaling in mediating hypertensive heart disease." in: Scientific reports, Vol. 8, Issue 1, pp. 8996, (2018) (PubMed).

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show more references
抗原

COL1A1 (Collagen, Type I, alpha 1 (COL1A1))

别名

COL1A1 (COL1A1 产品)

别名

OI4 antibody, Col1a-1 antibody, Cola-1 antibody, Cola1 antibody, Mov-13 antibody, Mov13 antibody, COLIA1 antibody, col1a1 antibody, MGC52532 antibody, COL1A1 antibody, COL1A2 antibody, alpha1(I) antibody, cb21 antibody, sb:cb21 antibody, sb:cb384 antibody, wu:fa99c12 antibody, wu:fb02c06 antibody, alpha3(I) antibody, col1a3 antibody, hm:zeh0348 antibody, wu:fa95h05 antibody, wu:fd02a10 antibody, wu:fj59a10 antibody, collagen type I alpha 1 chain antibody, collagen, type I, alpha 1 antibody, collagen, type I, alpha 1 S homeolog antibody, collagen alpha-1(I) chain antibody, collagen type I alpha 2 chain antibody, collagen, type I, alpha 1a antibody, collagen 1a1 antibody, collagen, type I, alpha 1b antibody, COL1A1 antibody, Col1a1 antibody, col1a1.S antibody, LOC397571 antibody, COL1A2 antibody, col1a1a antibody, col1a1 antibody, col1a1b antibody

背景

Collagen, type I, alpha 1, also known as COL1A1, is a human gene that encodes the major component of type I collagen, the fibrillar collagen found in most connective tissues, including cartilage. This gene is mapped to 17q21.33. And this gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis.

Synonyms: Alpha 1 type I collagen | Alpha 2 type I collagen | Alpha-1 type I collagen | CO1A1 | COL1A1 | Collagen alpha-1 chain | Collagen alpha1(I) chain | Collagen alpha-1(I) chain | Collagen I | Collagen Type 1 | Collagen type I alpha 1 | Collagen type I alpha 2 | collagen, type I, alpha 1 | OI4 | Pro alpha 1(I) collagen | Type I procollagen | P02452

基因ID

1277

UniProt

P02452

途径

Sensory Perception of Sound, Autophagy, Growth Factor Binding