COL1A1 抗体 (AA 100-200)
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北京 101111
Quick Overview for COL1A1 抗体 (AA 100-200) (ABIN6138837)
抗原
See all COL1A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-200
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序列
- ESPTDQETTG VEGPKGDTGP RGPRGPAGPP GRDGIPGQPG LPGPPGPPGP PGPPGLGGNF APQLSYGYDE KSTGGISVPG PMGPSGPRGL PGPPGAPGPQ G
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 100-200 of human COL1A1 (NP_000079.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
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别名
- COL1A1
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背景
- This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.,COL1A1,EDSC,OI1,OI2,OI3,OI4,COL1A1
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分子量
- 138 kDa
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基因ID
- 1277
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UniProt
- P02452
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途径
- Sensory Perception of Sound, Autophagy, Growth Factor Binding
抗原
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