COL1A1 抗体 (C-Term)
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北京 101111
Quick Overview for COL1A1 抗体 (C-Term) (ABIN5518708)
抗原
See all COL1A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1192-1207, C-Term
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原理
- Anti-Collagen I/COL1A1 Antibody
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序列
- QPPQEKSQDG GRYYRA
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Collagen I/COL1A1 Antibody (ABIN5518708). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse Collagen I, identical to the related rat sequence, and different from the related human sequence by two amino acids.
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亚型
- IgG
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anti-Collagen, Type I, alpha 1 (COL1A1) (AA 253-471) antibody
COL1A1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type I, alpha 1 (COL1A1) (AA 1225-1453) antibodyCOL1A1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type I, alpha 1 (COL1A1) (AA 1218-1440) antibodyCOL1A1 适用: 人 WB 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Collagen, Type I, alpha 1 (COL1A1) (AA 100-200) antibodyCOL1A1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type I, alpha 1 (COL1A1) (AA 253-471) antibodyCOL1A1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Collagen, Type I, alpha 1 (COL1A1) antibody (Biotin)COL1A1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IP, FACS, DB, MA 宿主: 兔 Polyclonal Biotin
anti-Collagen, Type I, alpha 1 (COL1A1) antibody (FITC)COL1A1 适用: 人, 大鼠, 小鼠, Cow WB, IHC, ELISA, IP, FACS 宿主: 兔 Polyclonal FITC
anti-Collagen, Type I, alpha 1 (COL1A1) (AA 1021-1108) antibodyCOL1A1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G3 unconjugated
anti-Collagen, Type I, alpha 1 (COL1A1) (AA 1219-1464) antibodyCOL1A1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7B1G12 unconjugated
anti-Collagen, Type I, alpha 1 (COL1A1) antibody (HRP)COL1A1 适用: 人, 大鼠, 小鼠, Cow WB, IHC, ELISA, IP, FACS 宿主: 兔 Polyclonal HRP
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence , 5 μg/mL, Mouse
Immunofluorescence, 5 μg/mL, Human, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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"Retraction: Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192465, (2018) (PubMed).
: "Nano-hydroxyapatite/collagen film as a favorable substrate to maintain the phenotype and promote the growth of chondrocytes cultured in vitro." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 2150-2158, (2018) (PubMed).
: "Adenovirus‑mediated knockdown of activin A receptor type 2A attenuates immune‑induced hepatic fibrosis in mice and inhibits interleukin‑17‑induced activation of primary hepatic stellate cells." in: International journal of molecular medicine, Vol. 42, Issue 1, pp. 279-289, (2018) (PubMed).
: "An essential role for Wnt/β-catenin signaling in mediating hypertensive heart disease." in: Scientific reports, Vol. 8, Issue 1, pp. 8996, (2018) (PubMed).
: "In vitro differentiation of endometrial regenerative cells into smooth muscle cells: Α potential approach for the management of pelvic organ prolapse." in: International journal of molecular medicine, Vol. 38, Issue 1, pp. 95-104, (2017) (PubMed).
: "Dimethyl α-ketoglutarate reduces CCl4-induced liver fibrosis through inhibition of autophagy in hepatic stellate cells." in: Biochemical and biophysical research communications, Vol. 481, Issue 1-2, pp. 90-96, (2017) (PubMed).
: "Beneficial effects of sulfonamide‑based gallates on osteoblasts in vitro." in: Molecular medicine reports, Vol. 15, Issue 3, pp. 1149-1156, (2017) (PubMed).
: "Erratum: Long-term intravenous administration of carboxylated single-walled carbon nanotubes induces persistent accumulation in the lungs and pulmonary fibrosis via the nuclear factor-kappa B pathway ..." in: International journal of nanomedicine, Vol. 12, pp. 1515, (2017) (PubMed).
: "miR-21 enhances cardiac fibrotic remodeling and fibroblast proliferation via CADM1/STAT3 pathway." in: BMC cardiovascular disorders, Vol. 17, Issue 1, pp. 88, (2017) (PubMed).
: "Protective effects of baicalin on rabbit articular chondrocytes in vitro." in: Experimental and therapeutic medicine, Vol. 13, Issue 4, pp. 1267-1274, (2017) (PubMed).
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: "Hesperetin alleviates renal interstitial fibrosis by inhibiting tubular epithelial-mesenchymal transition in vivo and in vitro." in: Experimental and therapeutic medicine, Vol. 14, Issue 4, pp. 3713-3719, (2017) (PubMed).
: "Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress and corporal fibrosis." in: Asian journal of andrology, Vol. 20, Issue 2, pp. 166-172, (2017) (PubMed).
: "FOXA2 alleviates CCl4-induced liver fibrosis by protecting hepatocytes in mice." in: Scientific reports, Vol. 7, Issue 1, pp. 15532, (2017) (PubMed).
: "hsa-miR-29c-3p regulates biological function of colorectal cancer by targeting SPARC." in: Oncotarget, Vol. 8, Issue 61, pp. 104508-104524, (2017) (PubMed).
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: "The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-β1 pathway." in: Scientific reports, Vol. 6, pp. 29975, (2018) (PubMed).
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- COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
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别名
- COL1A1
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背景
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Synonyms: Collagen alpha-1 (I) chain,Alpha-1 type I collagen,Col1a1,Cola1,
Tissue Specificity: Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.
Background: Collagen, type I, alpha 1, also known as COL1A1, is a human gene that encodes the major component of type I collagen, the fibrillar collagen found in most connective tissues, including cartilage. This gene is mapped to 17q21.33. This gene encodes the < a href="https://www.bosterbio.com/human-pro-collagen-i-alpha-1-col1a1-picokine-trade-elisa-kit-ek1692-boster.html" style="color:#EA8D28">pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis.
Sequence Similarities: Belongs to the fibrillar collagen family.
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分子量
- 130 kDa, 220 kDa
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UniProt
- P11087
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途径
- Sensory Perception of Sound, Autophagy, Growth Factor Binding
抗原
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