COL1A1 抗体 (AA 1219-1464)
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北京 101111
Quick Overview for COL1A1 抗体 (AA 1219-1464) (ABIN7193472)
抗原
See all COL1A1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1219-1464
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原理
- COL1A1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human COL1A1 (AA: 1219-1464) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
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别名
- COL1A1
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背景
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This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
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分子量
- 139 kDa
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基因ID
- 1277
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UniProt
- P02452
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途径
- Sensory Perception of Sound, Autophagy, Growth Factor Binding
抗原
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