CHEK1 抗体 (AA 312-327)
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Quick Overview for CHEK1 抗体 (AA 312-327) (ABIN401324)
抗原
See all CHEK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 312-327
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特异性
- This antibody is directed against yeast CHK1 protein.
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纯化方法
- Affinity chromatography
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免疫原
- Synthetic peptide corresponding aa 312-327 of S. cerevisiae CHK1
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亚型
- IgG
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应用备注
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ELISA: 1/2,000 - 1/10,000. Western Blot: 1/200 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.73 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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别名
- CHK1
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背景
- CHK1 (also known as serine/threonine-protein kinase CHK1 and checkpoint kinase 1) is involved in cell cycle arrest when DNA damage has occurred or when unligated DNA is present. The kinase controls phosphorylation and abundance of PDS1 to prevent anaphase entry. Also helps prevent mitotic exit. CHK1 is localized within the nucleus.Synonyms: CHEK-1, CHEK1, CHK1 checkpoint homolog, Serine/threonine-protein kinase Chk1
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基因ID
- 852577
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NCBI登录号
- NP_009833
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UniProt
- P38147
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途径
- p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
抗原
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