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TBP 抗体 (AA 210-239)

TBP 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB20259 unconjugated
产品编号 ABIN390631
发货至: 中国
  • 抗原 See all TBP 抗体
    TBP (TATA Box Binding Protein (TBP))
    抗原表位
    • 15
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 210-239
    适用
    • 68
    • 41
    • 39
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 50
    • 18
    • 2
    克隆类型
    • 50
    • 20
    多克隆
    标记
    • 50
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TBP antibody is un-conjugated
    应用范围
    • 63
    • 27
    • 14
    • 13
    • 12
    • 11
    • 10
    • 9
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    预测反应
    Zf, X, B, C, Pr, M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This TBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of human TBP.
    克隆位点
    RB20259
    亚型
    Ig Fraction
    Top Product
    Discover our top product TBP Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    TBP (TATA Box Binding Protein (TBP))
    别名
    TBP (TBP 产品)
    别名
    GTF2D antibody, GTF2D1 antibody, HDL4 antibody, SCA17 antibody, TFIID antibody, Gtf2d antibody, fd20h06 antibody, si:zc101n13.2 antibody, wu:fd20h06 antibody, zgc:66213 antibody, TBP1 antibody, TBP antibody, tbp antibody, CG9874 antibody, Dmel\\CG9874 antibody, RBP antibody, TBP38 antibody, TFIIDtau antibody, TfIID antibody, dTBP antibody, dTFIID antibody, dTbp antibody, dtbp antibody, gtf2d antibody, gtf2d1 antibody, sca17 antibody, tfiid antibody, tfiidtau antibody, xtbp antibody, tbp-a antibody, tbp-b antibody, TATA-box binding protein antibody, TATA box binding protein antibody, TATA binding protein antibody, TATA-box binding protein L homeolog antibody, TATA-box-binding protein antibody, TATA-box binding protein S homeolog antibody, TBP antibody, Tbp antibody, tbp antibody, tbp.L antibody, tbp.S antibody
    背景
    Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. A distinctive feature of TBP is a long string of glutamines in the N-terminal. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. Mutations that expand the number of CAG repeats encoding this polyglutamine tract, and thus increase the length of the polyglutamine string, are associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.
    分子量
    37698
    基因ID
    6908
    NCBI登录号
    NP_001165556, NP_003185
    UniProt
    P20226
    途径
    WNT signaling
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