电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

AKT3 抗体 (pSer472)

AKT3 适用: 人 DB 宿主: 兔 Polyclonal RB13331 unconjugated
产品编号 ABIN389853
发货至: 中国
  • 抗原 See all AKT3 抗体
    AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
    抗原表位
    • 13
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer472
    适用
    • 106
    • 52
    • 43
    • 11
    • 10
    • 9
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 83
    • 25
    • 1
    克隆类型
    • 74
    • 35
    多克隆
    标记
    • 55
    • 9
    • 8
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKT3 antibody is un-conjugated
    应用范围
    • 89
    • 57
    • 39
    • 15
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Dot Blot (DB)
    预测反应
    M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This AKT3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S472 of human AKT3.
    克隆位点
    RB13331
    亚型
    Ig Fraction
    Top Product
    Discover our top product AKT3 Primary Antibody
  • 应用备注
    DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Liu, Huang, Ren, Wen, Liu, Yang, Wang, Zhu, Zeng, Feng, Zhang, Chen, Jia, Zhang, Xia, Chen: "Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-?B and PI3K/Akt3 signaling pathways." in: Scientific reports, Vol. 5, pp. 11614, (2015) (PubMed).

    Yang, Xiong, Luo, Yang, Xi: "8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 37, Issue 1, pp. 361-74, (2015) (PubMed).

    Li, Jia, Ren, Liu, Gong, Wang, Zhang, Zhao: "Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma." in: IUBMB life, Vol. 66, Issue 7, pp. 507-18, (2014) (PubMed).

    Huang, Gonzalez, Toy, Banerjee, Kleer: "Blockade of CCN6 (WISP3) activates growth factor-independent survival and resistance to anoikis in human mammary epithelial cells." in: Cancer research, Vol. 70, Issue 8, pp. 3340-50, (2010) (PubMed).

    Silva, Garvin: "Akt1 mediates purinergic-dependent NOS3 activation in thick ascending limbs." in: American journal of physiology. Renal physiology, Vol. 297, Issue 3, pp. F646-52, (2009) (PubMed).

  • 抗原
    AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
    别名
    AKT3 (AKT3 产品)
    别名
    MPPH antibody, PKB-GAMMA antibody, PKBG antibody, PRKBG antibody, RAC-PK-gamma antibody, RAC-gamma antibody, STK-2 antibody, AI851531 antibody, D930002M15Rik antibody, Nmf350 antibody, Pkbg antibody, AKT serine/threonine kinase 3 antibody, thymoma viral proto-oncogene 3 antibody, v-akt murine thymoma viral oncogene homolog 3b antibody, AKT3 antibody, Akt3 antibody, akt3b antibody
    背景
    AKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).
    分子量
    55775
    基因ID
    10000
    NCBI登录号
    NP_001193658, NP_005456, NP_859029
    UniProt
    Q9Y243
    途径
    PI3K-Akt Signaling, RTK signaling, TLR signaling, Hepatitis C, VEGF Signaling
You are here:
客服