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SGK1 抗体 (N-Term)

SGK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043433
发货至: 中国
  • 抗原 See all SGK1 抗体
    SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
    抗原表位
    • 20
    • 20
    • 16
    • 14
    • 9
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-55, N-Term
    适用
    • 138
    • 94
    • 76
    • 20
    • 17
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 123
    • 11
    • 4
    • 1
    克隆类型
    • 127
    • 12
    多克隆
    标记
    • 66
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
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    This SGK1 antibody is un-conjugated
    应用范围
    • 131
    • 57
    • 50
    • 44
    • 40
    • 29
    • 28
    • 22
    • 9
    • 7
    • 4
    • 3
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    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase Sgk1(SGK1) detection. Tested with WB in Human.
    序列
    MKQRRMGLND FIQKIANNSY ACKHPEVQ
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase Sgk1(SGK1) detection. Tested with WB in Human.
    Gene Name: serum/glucocorticoid regulated kinase 1
    Protein Name: Serine/threonine-protein kinase Sgk1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human SGK1 (28-55aa MKQRRMGLNDFIQKIANNSYACKHPEVQ), different from the related mouse sequence by three amino acids, and from the related rat sequence by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product SGK1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SGK1 is approximately 0.1 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Chang, Bok, Sun, Edwards, Huang: "Neuropsin Inactivation Has Protective Effects against Depressive-Like Behaviours and Memory Impairment Induced by Chronic Stress." in: PLoS genetics, Vol. 12, Issue 10, pp. e1006356, (2017) (PubMed).

  • 抗原
    SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
    别名
    SGK1 (SGK1 产品)
    别名
    SGK antibody, Sgk antibody, sgk-B antibody, sgk2 antibody, cb1083 antibody, sgk antibody, wu:fc20a09 antibody, sgk-A antibody, sgk1 antibody, sgk1-a antibody, sgk1-b antibody, serum/glucocorticoid regulated kinase 1 antibody, Serine/threonine-protein kinase sgk-1 antibody, serum/glucocorticoid regulated kinase 1 S homeolog antibody, serum/glucocorticoid regulated kinase 1 L homeolog antibody, SGK1 antibody, Sgk1 antibody, sgk-1 antibody, sgk1.S antibody, sgk1 antibody, sgk1.L antibody
    背景
    Serine/threonine-protein kinase Sgk1, also called SGK1, encodes a serine/threonine protein kinase that plays an important role in cellular stress response. By fluorescence in situ hybridization, this gene is mapped to 6q23.2. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

    Synonyms: Serine/threonine protein kinase SGK antibody|Serine/threonine protein kinase Sgk1 antibody| Serine/threonine-protein kinase Sgk1 antibody|Serum and glucocorticoid regulated kinase antibody|Serum/glucocorticoid regulated kinase 1 antibody|Serum/glucocorticoid regulated kinase antibody|Serum/glucocorticoid-regulated kinase 1 antibody|SGK 1 antibody|SGK antibody|SGK1 antibody|SGK1_HUMAN antibody
    基因ID
    6446
    UniProt
    O00141
    途径
    MAPK Pathway, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
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