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ATM 抗体 (AA 2870-3056)

ATM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030031
发货至: 中国
  • 抗原 See all ATM 抗体
    ATM (Ataxia Telangiectasia Mutated (ATM))
    抗原表位
    • 30
    • 16
    • 15
    • 13
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2870-3056
    适用
    • 146
    • 74
    • 32
    • 1
    • 1
    • 1
    宿主
    • 128
    • 19
    • 5
    • 2
    克隆类型
    • 124
    • 30
    多克隆
    标记
    • 71
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This ATM antibody is un-conjugated
    应用范围
    • 65
    • 45
    • 39
    • 32
    • 28
    • 23
    • 21
    • 18
    • 17
    • 10
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Human partial recombinant protein (AA 2870-3056) was used as the immunogen for this ATM antibody.
    亚型
    IgG
    Top Product
    Discover our top product ATM Primary Antibody
  • 应用备注
    Titration of the ATM antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    The lyophilized ATM antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    ATM (Ataxia Telangiectasia Mutated (ATM))
    别名
    ATM (ATM 产品)
    别名
    ATM antibody, Atm antibody, CG6535 antibody, Dmel\\CG6535 antibody, Tefu antibody, atm antibody, atm/tefu antibody, dATM antibody, tef antibody, Xatm antibody, at1 antibody, atdc antibody, tel1 antibody, telo1 antibody, AT1 antibody, ATA antibody, ATC antibody, ATD antibody, ATDC antibody, ATE antibody, TEL1 antibody, TELO1 antibody, AI256621 antibody, C030026E19Rik antibody, telomere fusion antibody, ATM serine/threonine kinase L homeolog antibody, ATM serine/threonine kinase antibody, ataxia telangiectasia mutated antibody, ataxia telangiectasia mutated (atm) antibody, serine/threonine-protein kinase ATM antibody, tefu antibody, atm.L antibody, atm antibody, ATM antibody, EDI_100660 antibody, CpipJ_CPIJ001772 antibody, BDBG_08252 antibody, PAAG_02532 antibody, MCYG_05088 antibody, VDBG_06833 antibody, ACLA_015700 antibody, LOC5565620 antibody, MGYG_07634 antibody, PGTG_14279 antibody, Atm antibody
    背景
    Ataxia telangiectasia mutated, also known as TEL1 or TELO1, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. The ATM protein is a member of the phosphatidylinositol 3-kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control. The gene is mapped to chromosome 11q22.3. ATM has an essential role in the reconstitutive capacity of hematopoietic stem cells but is not as important for the proliferation or differentiation of progenitors in a telomere-independent manner. It functions directly in the repair of chromosomal DNA double-stranded breaks by maintaining DNA ends in repair complexes generated during lymphocyte gene assembly.
    基因ID
    472
    途径
    p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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