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Retinoblastoma 1 抗体 (pSer811)
RB1
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
Retinoblastoma 1抗体详情
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抗原
See all Retinoblastoma 1 (RB1) 抗体
Retinoblastoma 1 (RB1)
抗原表位
All epitopes for Retinoblastoma 1 抗体
pSer811
适用
All reactivities for Retinoblastoma 1 抗体
人
宿主
All hosts for Retinoblastoma 1 抗体
兔
克隆类型
All clonalities for Retinoblastoma 1 抗体
多克隆
标记
All conjugates for Retinoblastoma 1 抗体
This Retinoblastoma 1 antibody is un-conjugated
应用范围
All applications for Retinoblastoma 1 抗体
Western Blotting (WB)
序列
LKSPY
交叉反应
人
产品特性
Phosphorylated Antibodies
纯化方法
Affinity purification
免疫原
A synthetic phosphorylated peptide around S811 of human RB (NP_000312.2).
亚型
IgG
Top Product
Discover our top product RB1 Primary Antibody
Alternatives
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使用细节
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应用备注
WB,1:1000 - 1:2000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid freeze / thaw cycles
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
References for anti-Retinoblastoma 1 antibody (ABIN3023610)
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Wu, Lv, He, Zhang, Mei, Cui, Huang, Xie, Xu, Zhang : "MicroRNA-188 suppresses G1/S transition by targeting multiple cyclin/CDK complexes. " in: Cell communication and signaling : CCS , Vol. 12 , pp. 66 , (2015 ) (PubMed ).
Retinoblastoma 1目标详情
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抗原
Retinoblastoma 1 (RB1)
别名
RB1 (RB1 产品 )
别名
OSRC antibody, RB antibody, p105-Rb antibody, pRb antibody, pp110 antibody, Rb antibody, Rb-1 antibody, P105-RB antibody, PP110 antibody, RB11 antibody, zgc:154147 antibody, RB transcriptional corepressor 1 antibody, RB transcriptional corepressor like 1 antibody, retinoblastoma 1 antibody, RB1 antibody, RBL1 antibody, Rb1 antibody, rb1 antibody
背景
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.,OSRC,PPP1R130,RB,p105-Rb,pRb,pp110,RB1,Rb,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G1/S Checkpoint,Protein phosphorylation,RB1
分子量
106 kDa
基因ID
5925
UniProt
P06400
途径
Cell Division Cycle , Intracellular Steroid Hormone Receptor Signaling Pathway , Mitotic G1-G1/S Phases , DNA Replication , Maintenance of Protein Location , Synthesis of DNA , Autophagy
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