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GRB2 抗体 (AA 198-217)

GRB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN302091
发货至: 中国
  • 抗原 See all GRB2 抗体
    GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
    抗原表位
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 198-217
    适用
    • 62
    • 30
    • 29
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 50
    • 9
    • 3
    克隆类型
    • 51
    • 10
    • 1
    多克隆
    标记
    • 43
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRB2 antibody is un-conjugated
    应用范围
    • 47
    • 33
    • 18
    • 12
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The polyclonal antibody recognizes Grb2, a highly conserved approximately 26 kDa intracellular adaptor protein. The immunogen has 100 % identity between man, cow, rat and mouse.
    交叉反应 (详细)
    Human, Other species Not tested
    纯化方法
    Purified by ligand affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Synthetic peptide corresponding to C-terminus of human Grb2 (amino acids 198-217).
    Top Product
    Discover our top product GRB2 Primary Antibody
  • 应用备注
    Western blotting: Recommended dilution: 1-2 μg/mL, reducing conditions.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
    别名
    Grb2 (GRB2 产品)
    别名
    GRB2 antibody, grb2 antibody, AA408164 antibody, Ash antibody, ASH antibody, EGFRBP-GRB2 antibody, Grb3-3 antibody, MST084 antibody, MSTP084 antibody, NCKAP2 antibody, wu:fb18e12 antibody, wu:fb34e06 antibody, zgc:73077 antibody, growth factor receptor bound protein 2 antibody, growth factor receptor-bound protein 2 antibody, growth factor receptor-bound protein 2b antibody, GRB2 antibody, grb2 antibody, Grb2 antibody, grb2b antibody
    背景
    Growth factor receptor bound protein 2,Grb2 (growth factor receptor-bound protein 2) is a highly conserved adaptor protein composed of central SH2 domain flanked by two terminal SH3 domains. Grb2 mediates coupling of receptor protein tyrosine kinases to a guanine nucleotide exchange factor Sos, thereby enabling the tyrosine kinases to stimulate activity of Ras and hence of MAP kinase pathway. Grb2 also can bind to receptor protein tyrosine phosphatases and affect their signaling.,ASH, NCKAP2
    基因ID
    2885
    UniProt
    P62993
    途径
    RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation
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