电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

ATM 抗体 (pSer1981)

ATM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3019429
发货至: 中国
  • 抗原 See all ATM 抗体
    ATM (Ataxia Telangiectasia Mutated (ATM))
    抗原表位
    • 30
    • 16
    • 15
    • 13
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1981
    适用
    • 153
    • 79
    • 32
    • 3
    • 2
    • 1
    • 1
    宿主
    • 134
    • 19
    • 6
    • 2
    克隆类型
    • 129
    • 32
    多克隆
    标记
    • 77
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This ATM antibody is un-conjugated
    应用范围
    • 70
    • 46
    • 39
    • 33
    • 28
    • 25
    • 21
    • 20
    • 18
    • 11
    • 8
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    EGSQS
    交叉反应
    人, 小鼠
    产品特性
    Phosphorylated Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic phosphorylated peptide around S1981 of human ATM (NP_000042.3).
    亚型
    IgG
    Top Product
    Discover our top product ATM Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ATM (Ataxia Telangiectasia Mutated (ATM))
    别名
    ATM (ATM 产品)
    别名
    ATM antibody, Atm antibody, CG6535 antibody, Dmel\\CG6535 antibody, Tefu antibody, atm antibody, atm/tefu antibody, dATM antibody, tef antibody, Xatm antibody, at1 antibody, atdc antibody, tel1 antibody, telo1 antibody, AT1 antibody, ATA antibody, ATC antibody, ATD antibody, ATDC antibody, ATE antibody, TEL1 antibody, TELO1 antibody, AI256621 antibody, C030026E19Rik antibody, telomere fusion antibody, ATM serine/threonine kinase L homeolog antibody, ATM serine/threonine kinase antibody, ataxia telangiectasia mutated antibody, ataxia telangiectasia mutated (atm) antibody, serine/threonine-protein kinase ATM antibody, tefu antibody, atm.L antibody, atm antibody, ATM antibody, EDI_100660 antibody, CpipJ_CPIJ001772 antibody, BDBG_08252 antibody, PAAG_02532 antibody, MCYG_05088 antibody, VDBG_06833 antibody, ACLA_015700 antibody, LOC5565620 antibody, MGYG_07634 antibody, PGTG_14279 antibody, Atm antibody
    背景
    The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.,AT1,ATA,ATC,ATD,ATDC,ATE,TEL1,TELO1,ATM,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Phosphorylation,DNA Damage & Repair,Cancer,Tumor suppressors,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Cell Cycle,G1/S Checkpoint,G2/M DNA Damage Checkpoint,Immunology & Inflammation,NF-kB Signaling Pathway,Protein phosphorylation,ATM
    分子量
    350 kDa
    基因ID
    472
    UniProt
    Q13315
    途径
    p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
You are here:
客服