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C-JUN 抗体 (C-Term)

Name: C-JUN 抗体 (C-Term)
SKU: ABIN2792667
Availability: OutOfStock

This anti-C-JUN antibody is a 兔多克隆 antibody detecting C-JUN in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 绵羊, 斑马鱼和豚鼠.

WB Suggested Anti-JUNB Antibody Titration: 2. (C-JUN 抗体 (C-Term))

2 images

产品编号 ABIN2792667

发货至: 中国

Datasheet as PDF

Quick Overview for C-JUN 抗体 (C-Term) (ABIN2792667)

抗原

See all C-JUN (JUN) 抗体

C-JUN (JUN) (Jun Proto-Oncogene (JUN))

适用

人, 小鼠, 大鼠, Cow, 犬, 绵羊, 斑马鱼, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This C-JUN antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product JUN Primary Antibody

抗原表位
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28

20

16

16

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9

8

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7

7

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4

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3

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3

3

2

2

2

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2

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2

2

2

2

2

2

1

1

1

1

1

1

1

1
C-Term

序列

EEPQTVPEAR SRDATPPVSP INMEDQERIK VERKRLRNRL AATKCRKRKL

交叉反应

牛, 犬, 人, 小鼠, 大鼠

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

产品特性

This is a rabbit polyclonal antibody against JUNB. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human JUNB
anti-Jun Proto-Oncogene (JUN) (AA 31-331) antibody
JUN 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Jun Proto-Oncogene (JUN) (AA 1-70) antibody
JUN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Jun Proto-Oncogene (JUN) antibody
JUN 适用: 人, 小鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5B1 unconjugated

anti-Jun Proto-Oncogene (JUN) (pThr91) antibody
JUN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Jun Proto-Oncogene (JUN) (AA 1-70) antibody
JUN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Jun Proto-Oncogene (JUN) (N-Term) antibody
JUN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Jun Proto-Oncogene (JUN) antibody
JUN 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2D11 unconjugated

anti-Jun Proto-Oncogene (JUN) (pSer73) antibody
JUN 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Jun Proto-Oncogene (JUN) antibody
JUN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 9F5 unconjugated

anti-Jun Proto-Oncogene (JUN) antibody
JUN 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Monoclonal 4A11 unconjugated

应用备注

WB Suggested Anti-JUNB Antibody Titration: 2.5 µg/mL
ELISA Titer: 1:62500
Positive Control: Transfected 293T.
Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 347 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

C-JUN (JUN) (Jun Proto-Oncogene (JUN))

别名

Jun

背景

The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. JunB is involved in many types of human carcinoma including T-cell lymphomas, CML,primary cutaneous lymphomas. Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction.JunB is an important regulator of erythroid Differentiation.
Alias Symbols: AP-1
Protein Interaction Partner: BATF, FOS, RFWD2, C19orf68, USP24, TCERG1, ZNF595, PKIA, MAP2, APLP2, FOSL1, DDIT3, ATF3, BATF2, BATF3, TCL1A, FOSL2, NPM1, NEU1, SMAD4, HOXA7, BDNF, ATF4, MAPK6, UBC, TDG, SET, SAT1, MAPK9, BRCA1, SUMO2, Cebpb, EP300, SMURF1, YY1, CREBBP, SMARCA4, JDP2,
Protein Size: 347

分子量

36 kDa

基因ID

3726

NCBI登录号

NM_002229, NP_002220

UniProt

P17275

途径

MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins