NR3C2 抗体 (C-Term)
-
- 抗原 See all NR3C2 抗体
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
-
抗原表位
- C-Term
-
适用
- 人, 大鼠, 小鼠, 马, Cow
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This NR3C2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- VSDLLEFCFY TFRESHALKV EFPAMLVEII SDQLPKVESG NAKPLYFHRK
- 交叉反应
- 小鸡, 人, 小鼠, 大鼠
- 预测反应
- Cow: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against NR3C2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NR3C2
- Top Product
- Discover our top product NR3C2 Primary Antibody
-
-
- 应用备注
-
WB Suggested Anti-NR3C2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:12500
Positive Control: PANC1 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - 说明
-
Antigen size: 867 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
- 别名
- NR3C2 (NR3C2 产品)
- 别名
- mr antibody, si:ch211-189l17.1 antibody, LOC100302443 antibody, NR3C2 antibody, LOC443144 antibody, MLR antibody, MR antibody, MCR antibody, NR3C2VIT antibody, Mlr antibody, mlr antibody, nuclear receptor subfamily 3, group C, member 2 antibody, nuclear receptor subfamily 3 group C member 2 antibody, mineralocorticoid receptor antibody, nuclear receptor subfamily 3 group C member 2 L homeolog antibody, nr3c2 antibody, NR3C2 antibody, LOC443144 antibody, Nr3c2 antibody, nr3c2.L antibody
- 背景
-
NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Alias Symbols: MR, MCR, MLR, FLJ41052, NR3C2VIT, MGC133092, NR3C2
Protein Interaction Partner: RABAC1, RXRA, HSP90AA1, ACSL1, UBC, SRC, PPP5C, PPID, FKBP5, FKBP4, STUB1, AIP, TRIM24, NRIP1, DNAJC7, CAND1, SUMO1, UBE2I, EIF3I, PROX1, PIAS1, PIAS3, HSPA4, PTGES3, AR, NR3C1, ACTA1, ACTG1,
Protein Size: 867 - 分子量
- 94 kDa
- 基因ID
- 4306
- NCBI登录号
- NM_001166104, NP_001159576
- UniProt
- B0ZBF5
- 途径
- ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
-