COL1A1 抗体 (C-Term)
-
- 抗原 See all COL1A1 抗体
- COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
-
抗原表位
- C-Term
-
适用
- 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This COL1A1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- YRADDANVVR DRDLEVDTTL KSLSQQIENI RSPEGSRKNP ARTCRDLKMC
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
- 产品特性
- This is a rabbit polyclonal antibody against COL1A1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human COL1A1
- Top Product
- Discover our top product COL1A1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 1464 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
- 别名
- COL1A1 (COL1A1 产品)
- 别名
- OI4 antibody, Col1a-1 antibody, Cola-1 antibody, Cola1 antibody, Mov-13 antibody, Mov13 antibody, COLIA1 antibody, col1a1 antibody, MGC52532 antibody, COL1A1 antibody, COL1A2 antibody, alpha1(I) antibody, cb21 antibody, sb:cb21 antibody, sb:cb384 antibody, wu:fa99c12 antibody, wu:fb02c06 antibody, alpha3(I) antibody, col1a3 antibody, hm:zeh0348 antibody, wu:fa95h05 antibody, wu:fd02a10 antibody, wu:fj59a10 antibody, collagen type I alpha 1 chain antibody, collagen, type I, alpha 1 antibody, collagen, type I, alpha 1 S homeolog antibody, collagen alpha-1(I) chain antibody, collagen type I alpha 2 chain antibody, collagen, type I, alpha 1a antibody, collagen 1a1 antibody, collagen, type I, alpha 1b antibody, COL1A1 antibody, Col1a1 antibody, col1a1.S antibody, LOC397571 antibody, COL1A2 antibody, col1a1a antibody, col1a1 antibody, col1a1b antibody
- 背景
-
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Alias Symbols: OI4
Protein Interaction Partner: PDGFB, PDGFA, COL1A2, COL1A1, CAPN1, UBC, BRCA1, BARD1, C12orf57, RNH1, ATP13A2, ELAVL1, ACHE, TMPRSS6, P4HB, PAK1, HTRA1, MATN2, PRELP, TGFBI, BGN, VWF, ITGA2, DDR2, THBS1, TXN, SPARC, CD36, FGF7, IGFBP3, ITGA5, FN1, NID1, DCN, CD93, MMP9, MMP2, COL7A1,
Protein Size: 1464 - 分子量
- 137 kDa
- 基因ID
- 1277
- NCBI登录号
- NM_000088, NP_000079
- UniProt
- P02452
- 途径
- Sensory Perception of Sound, Autophagy, Growth Factor Binding
-