电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

NR3C2 抗体 (Middle Region)

NR3C2 适用: 人, 大鼠, 小鼠, 马, Cow, Pig, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2773864
发货至: 中国
  • 抗原 See all NR3C2 抗体
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    抗原表位
    • 16
    • 15
    • 15
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 57
    • 44
    • 29
    • 17
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    人, 大鼠, 小鼠, 马, Cow, Pig, 兔, 豚鼠
    宿主
    • 69
    • 5
    克隆类型
    • 69
    • 5
    多克隆
    标记
    • 26
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This NR3C2 antibody is un-conjugated
    应用范围
    • 71
    • 39
    • 39
    • 20
    • 14
    • 12
    • 10
    • 8
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    RRKNCPACRL QKCLQAGMNL GARKSKKLGK LKGIHEEQPQ QQQPPPPPPP
    预测反应
    Cow: 83%, Guinea Pig: 75%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 100%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against NR3C2. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human NR3C2
    Top Product
    Discover our top product NR3C2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 984 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    别名
    NR3C2 (NR3C2 产品)
    别名
    mr antibody, si:ch211-189l17.1 antibody, LOC100302443 antibody, NR3C2 antibody, LOC443144 antibody, MLR antibody, MR antibody, MCR antibody, NR3C2VIT antibody, Mlr antibody, mlr antibody, nuclear receptor subfamily 3, group C, member 2 antibody, nuclear receptor subfamily 3 group C member 2 antibody, mineralocorticoid receptor antibody, nuclear receptor subfamily 3 group C member 2 L homeolog antibody, nr3c2 antibody, NR3C2 antibody, LOC443144 antibody, Nr3c2 antibody, nr3c2.L antibody
    背景
    NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
    Alias Symbols: MCR, MGC133092, MLR, MR, NR3C2VIT
    Protein Interaction Partner: RABAC1, RXRA, HSP90AA1, ACSL1, UBC, SRC, PPP5C, PPID, FKBP5, FKBP4, STUB1, AIP, TRIM24, NRIP1, DNAJC7, CAND1, SUMO1, UBE2I, EIF3I, PROX1, PIAS1, PIAS3, HSPA4, PTGES3, AR, NR3C1, ACTA1, ACTG1,
    Protein Size: 984
    分子量
    107 kDa
    基因ID
    4306
    NCBI登录号
    NM_000901, NP_000892
    UniProt
    P08235
    途径
    ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
You are here:
客服