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PTPN11 抗体

PTPN11 适用: 人, 犬 WB, FACS 宿主: 小鼠 Monoclonal 3F2 unconjugated
产品编号 ABIN2730107
发货至: 中国
  • 抗原 See all PTPN11 抗体
    PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
    适用
    • 154
    • 116
    • 105
    • 10
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    人, 犬
    宿主
    • 169
    • 14
    • 2
    • 1
    小鼠
    克隆类型
    • 149
    • 37
    单克隆
    标记
    • 88
    • 12
    • 9
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    This PTPN11 antibody is un-conjugated
    应用范围
    • 121
    • 50
    • 42
    • 27
    • 26
    • 26
    • 20
    • 16
    • 14
    • 7
    • 6
    • 3
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    Western Blotting (WB), Flow Cytometry (FACS)
    产品特性
    Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11)
    纯化方法
    Purified from mouse ascites fluids by affinity chromatography
    免疫原
    Full length human recombinant protein of human PTPN11(NP_002825) produced in HEK293T cell.
    克隆位点
    3F2
    亚型
    IgG2a
    Top Product
    Discover our top product PTPN11 Primary Antibody
  • 应用备注
    WB 1:500~2000, FLOW 1:100
    说明

    The concentration of the product may vary between diferrent lots.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5-1.0 mg/mL
    缓冲液
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
    别名
    PTPN11 (PTPN11 产品)
    别名
    BPTP3 antibody, CFC antibody, NS1 antibody, PTP-1D antibody, PTP2C antibody, SH-PTP2 antibody, SH-PTP3 antibody, SHP2 antibody, 2700084A17Rik antibody, AW536184 antibody, PTP1D antibody, SAP-2 antibody, SHP-2 antibody, Shp2 antibody, Syp antibody, SYP antibody, bptp3 antibody, cfc antibody, ns1 antibody, ptp-2 antibody, ptp2c antibody, ptpn11 antibody, ptpn11-a antibody, ptpn11-b antibody, shp-2 antibody, shp2 antibody, fa14b09 antibody, wu:fa14b09 antibody, wu:fi24f03 antibody, zgc:55388 antibody, zgc:63553 antibody, protein tyrosine phosphatase, non-receptor type 11 antibody, protein tyrosine phosphatase, non-receptor type 11 S homeolog antibody, protein tyrosine phosphatase, non-receptor type 11, a antibody, protein tyrosine phosphatase, non-receptor type 11, b antibody, PTPN11 antibody, Ptpn11 antibody, ptpn11.S antibody, ptpn11a antibody, ptpn11b antibody
    物质类
    Viral Protein
    背景
    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
    分子量
    67.8 kDa
    基因ID
    5781
    NCBI登录号
    NM_002834
    HGNC
    5781
    途径
    JAK/STAT Signaling, RTK signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect
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